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Pathology (Pathoma) > Carcinogenic Agents (Pathoma) > Flashcards

Carcinogenic Agents (Pathoma) Flashcards

1
Q

Aflatoxins

A

Hepatocellular carcinoma

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2
Q

Alkylating Agents

A

Leukemia/Lymphoma

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3
Q

Alcohol

A

Squamous cell carcinoma of oropharynx and upper esophagus, and hepatocellular carcinoma

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4
Q

Arsenic

A

Squamous cell carcinoma of skin, lung cancer, and angiosarcoma of liver. (Present in cigarette smoke)

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5
Q

Asbestos

A

Lung carcinoma and mesothelioma. More likely to lead to lung cancer than mesothelioma!

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6
Q

Cigarette Smoke

A

Carcinoma of oropharynx, esophagus, lung, kidney, bladder, pancreas. Polycyclic hydrocarbons particularly carcinogenic.

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7
Q

Nitrosamines

A

Stomach carcinoma (found in smoked foods; explains Japan’s high rate)

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8
Q

Napthylamine

A

Urothelial carcinoma of bladder (Derived from cigarette smoke)

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9
Q

Vinyl Chloride

A

Angiosarcoma of liver

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10
Q

Nickel, chromium, beryllium, or silica

A

Lung carcinoma

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11
Q

EBV (Epstein-Barr virus)

A

Nasopharyngeal carcinoma, Burkitt lymphoma, and CNS lymphoma in AIDS

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12
Q

HHV-8 (Herpes)

A

Kaposi sarcoma

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13
Q

HBV and HCV (hepatitis)

A

Hepatocellular carcinoma

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14
Q

HTLV-1

A

Adult T-cell leukemia/lymphoma

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15
Q

High risk HPV (eg, 16, 18, 31, 33)

A

Squamous cell carcinoma of vulva, vagina, anus, and cervix; adenocarcinoma of cervix.

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16
Q

Ionizing radiation

A

AML, CML, papillary carcinoma of thyroid. (Generates hydroxyl free radicals)

17
Q

Nonionizing radiation (UVB)

A

Basal cell carcinoma, squamous cell carcinoma, and melanoma of skin. (Results in formation of pyrimidine dimers)

18
Q

Hepatocellular carcinoma

A

Aflatoxins

19
Q

Leukemia/Lymphoma

A

Alkylating Agents

20
Q

Squamous cell carcinoma of oropharynx and upper esophagus, and hepatocellular carcinoma

A

Alcohol

21
Q

Squamous cell carcinoma of skin, lung cancer, and angiosarcoma of liver. (Present in cigarette smoke)

A

Arsenic

22
Q

Lung carcinoma and mesothelioma. More likely to lead to lung cancer than mesothelioma!

A

Asbestos

23
Q

Carcinoma of oropharynx, esophagus, lung, kidney, bladder, pancreas. Polycyclic hydrocarbons particularly carcinogenic.

A

Cigarette Smoke

24
Q

Stomach carcinoma (found in smoked foods; explains Japan’s high rate)

A

Nitrosamines

25
Q

Urothelial carcinoma of bladder (Derived from cigarette smoke)

A

Napthylamine

26
Q

Angiosarcoma of liver

A

Vinyl Chloride

27
Q

Lung carcinoma

A

Nickel, chromium, beryllium, or silica

28
Q

Nasopharyngeal carcinoma, Burkitt lymphoma, and CNS lymphoma in AIDS

A

EBV (Epstein-Barr virus)

29
Q

Kaposi sarcoma

A

HHV-8 (Herpes)

30
Q

Hepatocellular carcinoma

A

HBV and HCV (hepatitis)

31
Q

Adult T-cell leukemia/lymphoma

A

HTLV-1

32
Q

Squamous cell carcinoma of vulva, vagina, anus, and cervix; adenocarcinoma of cervix.

A

High risk HPV (eg, 16, 18, 31, 33)

33
Q

AML, CML, papillary carcinoma of thyroid. (Generates hydroxyl free radicals)

A

Ionizing radiation

34
Q

Basal cell carcinoma, squamous cell carcinoma, and melanoma of skin. (Results in formation of pyrimidine dimers)

A

Nonionizing radiation (UVB)

Pathology (Pathoma) (1 decks)

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