Carcinogenesis Flashcards
1
Q
Categories of proto-oncogenes
A
- Growth factors
- Growth factor receptors
- Signal transducers
- Cell cycle regulators
2
Q
Aflatoxins associated with:
A
HCC
3
Q
Alkylating agents associated with:
A
Leukemia/lymphoma
4
Q
Alcohol associated with:
A
SCC of oropharynx, upper esophagus, HCC, pancreatic CA
5
Q
Arsenic associated with:
A
SCC of skin, lung CA, angiosarcoma of liver
6
Q
Asbestos associated with:
A
Lung CA and mesothelioma
7
Q
Cigarette smoke associated with:
A
SCC of oropharynx, esophagus, lung CA, urothelium (kidney, bladder), pancreas
8
Q
Nitrosamines found where and associated with:
A
Smoked foods Stomach CA (intestinal type)
9
Q
Naphthylamine associated with:
A
Urothelial CA of bladder
10
Q
Vinyl chloride associated with:
A
Angiosarcoma of liver
11
Q
Nickel, chromium, beryllium or silica can cx:
A
Lung CA
