Carboxylic Acids And Derivaties

Question 1

Base induced ester hydrolysis

Answer 1

Oh-

Ester- carboxylic acid

Question 2

1° alcohol- carboxylic acid

Answer 2

Jones reagent - h2 CrO4

Question 3

Aldehydes to carboxylic acid

Answer 3

Ag+ (NH3)2

Question 4

Carboxylic acid - alchol

Answer 4

Lialh4 and h3O+

Question 5

Esters with alkyl halides

Answer 5

Carboxylic acid froms acetate anion
Reacts with delta positive c on side chain of ring
Forms ester

Question 6

Creating carboxylic acid using grignard

Answer 6

Use carbon dioxide

And h3O+ as source of hydrogen

Question 7

Carboxylic acid - acid chloride

Answer 7

Thionyl chloride (SOCL2) - good leaving group

Question 8

Carboxylic acid to anhydride

Answer 8

Carboxylic acid + acid chloride

Hcl produced

Question 9

Carboxylic acid - ester

Answer 9

Activation of C=O
Nucleophilic addition
Transfer of proton converting oh to h2o
Loss of h2o and regeneration of h+

Question 10

What mechanism is used to convert Acid chloride - amide

Answer 10

Nucleophilic substitution

Question 11

Amide to carboxylic acid

Answer 11

Hydrolysis

Forms ammonia= good leaving group

Question 12

Amide - amine

Answer 12

Reduction by LIALH4 (H-ALH3)