Carbonic Anhydrase Inhibitors Flashcards
What is the primary action of carbonic anhydrase inhibitors?
To inhibit the enzyme carbonic anhydrase, leading to decreased bicarbonate reabsorption in the kidneys.
True or False: Carbonic anhydrase inhibitors are primarily used to treat hypertension.
False
Fill in the blank: The most common carbonic anhydrase inhibitor used in clinical practice is ______.
Acetazolamide
What is a common indication for the use of carbonic anhydrase inhibitors?
Glaucoma
Multiple Choice: Which of the following is NOT a route of administration for carbonic anhydrase inhibitors? A) Oral B) Intravenous C) Inhalation D) Subcutaneous
D) Subcutaneous
What are the potential adverse effects of carbonic anhydrase inhibitors?
Metabolic acidosis, hypokalemia, renal stones, and allergic reactions.
True or False: Carbonic anhydrase inhibitors can cause respiratory acidosis.
False
Short Answer: What nursing implication should be monitored when a patient is on carbonic anhydrase inhibitors?
Electrolyte levels, particularly potassium.
Fill in the blank: Carbonic anhydrase inhibitors can lead to ______ due to increased bicarbonate excretion.
Metabolic acidosis
Multiple Choice: Which of the following conditions is a contraindication for carbonic anhydrase inhibitors? A) Chronic obstructive pulmonary disease B) Liver disease C) Severe renal impairment D) Diabetes
C) Severe renal impairment
What effect do carbonic anhydrase inhibitors have on intraocular pressure?
They lower intraocular pressure.
True or False: Carbonic anhydrase inhibitors can be used in the treatment of altitude sickness.
True
Short Answer: What should be assessed before administering carbonic anhydrase inhibitors?
The patient’s renal function.
Fill in the blank: Carbonic anhydrase inhibitors may lead to ______ due to their diuretic effect.
Dehydration
Multiple Choice: Which electrolyte imbalance is commonly associated with carbonic anhydrase inhibitors? A) Hyperkalemia B) Hyponatremia C) Hypokalemia D) Hypercalcemia
C) Hypokalemia
What is the mechanism by which carbonic anhydrase inhibitors reduce fluid accumulation?
By decreasing bicarbonate and sodium reabsorption in the proximal renal tubule.
True or False: Carbonic anhydrase inhibitors are effective in treating heart failure.
False
Short Answer: What is a common side effect of acetazolamide?
Tingling of the fingers and toes.
Fill in the blank: The therapeutic effect of carbonic anhydrase inhibitors is primarily due to their action on the ______.
Kidneys
Multiple Choice: Which of the following is a potential drug interaction with carbonic anhydrase inhibitors? A) NSAIDs B) Antihypertensives C) Diuretics D) All of the above
D) All of the above
What is the primary clinical use of carbonic anhydrase inhibitors in ophthalmology?
To treat open-angle glaucoma.
True or False: Carbonic anhydrase inhibitors can be used to enhance the excretion of certain drugs.
True
Short Answer: Which patient population should use carbonic anhydrase inhibitors with caution?
Patients with a history of kidney stones.
Fill in the blank: Carbonic anhydrase inhibitors may cause ______ in patients with sulfa allergies.
Allergic reactions
