Carbohydrates & Glycolysis Flashcards

0
Q

compounds that differ in configuration around ONLY ONE specific carbon atom with exceptin of the carboxyl carbon

A

Epimers

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1
Q

compounds that have same chemical formula but different structures
C6H12O6

A

Isomers

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2
Q

pairs of structures that are MIRROR Image of each other ..

are designated as D-sugar and L-sugar

A

Enantiomers

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3
Q

sugars are convertible between linear form and ring form

most are in th cyclic or ring form

A

anomers

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4
Q

can convert spontaneously through process

no need enzyme

A

mutarotation

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5
Q

transporter in all sugar

facilitated diffusion

A

GLUT 2

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6
Q

transporter occurs in GUT kidneys

fxn: absorption of Fructose, glucose, galactose

A

GLUT 5

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7
Q

secondary active transport
Na / hexose symporter
for glucose and galactose

A

SGLT 1

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8
Q

glycemic index

low glycemic index is beneficial in DM AND DIETING

A

inc in blood glucose after a test dose of a CHO compared with that after equivalent amt of glucose
tells how fast absorption

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9
Q

example of anabolic - synthesis of compound from smaller raw materials

A

CHON and triglycerides synthesis, glycogenesis

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10
Q

example of catabolic - breakdown of larger molecules

A

glycolysis, beta oxidation, glycogenolysis

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11
Q

example of amphibolic

A

citric acid cycle

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12
Q

second messenger of insulin and growth factor

A

tyrosine kinase

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13
Q

2nd msgr that activate CHON kinase C and release intracellilar Ca

A

DAG, inositol triphosphate

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14
Q

Transporter all tissues esp red cell brain

A

GLUT 1

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15
Q

transporter for brain

A

GLUT 1 & 3

16
Q

differentiate 2types of glycolysis

A

aerobic - cells with mitochondria and adequate O2 supply,
PYRUVATE, ex. resting muscle
anaerobic - cells without ….
LACTATE ex. rbc, exercising muscle cramps…

17
Q

rate limiting reaction of glycolytic pathway, pace setting enzyme of glycolysis

18
Q

fxn of PKF 2?

A

converts F-6-P to F-2,6-BP, activate to enhance PFK 1

19
Q

is the second most common cause ( after glucose 6 phospate DH deficiency) of enzyme def. related chronic HEMOLYTIC ANEMIA
most common enzyme defect in glycolysis

A

Pyruvate kinase deficiency

20
Q

how many net mol. of ATP can be produced from 1 glucose mol. via substrate - level phosphorylation?

A

2 ATP molecules

21
Q

in what part of the cell can you find the electron transport chain

A

inner mitochondrial mem.

22
Q

activator of PFK 1?

inhibitor?

A

activator: F 2,6 BP & AMP
inhibitor: ATP & citrate

23
Q

found in RBC where phosphoglycerate kinase is bypassed,
it is also binds to hgb to let go oxygen. “kabit” to let go oxygen.. higher altitude environment so oxygen will release..

A

2,3 Bisphosphoglycerate

24
inhibits pyruvate DH by binding to lipoic acid
arsenic poisoning
25
most common biochemical cause of congenital lactic acidosis x-linked dominant condition, inc. lactate, dec acetyl CoA. tx. ketogenic diet
Pyruvate dehydrogenase deficiency
26
co enzyme of conversion of pyruvate to acetyl CoA?
lipoic acid, NAD, FAD, Thiamine pyrophosphate, Coenzyme A - pantothenic acid