Carbohydrates & Glycolysis Flashcards

0
Q

compounds that differ in configuration around ONLY ONE specific carbon atom with exceptin of the carboxyl carbon

A

Epimers

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1
Q

compounds that have same chemical formula but different structures
C6H12O6

A

Isomers

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2
Q

pairs of structures that are MIRROR Image of each other ..

are designated as D-sugar and L-sugar

A

Enantiomers

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3
Q

sugars are convertible between linear form and ring form

most are in th cyclic or ring form

A

anomers

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4
Q

can convert spontaneously through process

no need enzyme

A

mutarotation

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5
Q

transporter in all sugar

facilitated diffusion

A

GLUT 2

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6
Q

transporter occurs in GUT kidneys

fxn: absorption of Fructose, glucose, galactose

A

GLUT 5

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7
Q

secondary active transport
Na / hexose symporter
for glucose and galactose

A

SGLT 1

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8
Q

glycemic index

low glycemic index is beneficial in DM AND DIETING

A

inc in blood glucose after a test dose of a CHO compared with that after equivalent amt of glucose
tells how fast absorption

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9
Q

example of anabolic - synthesis of compound from smaller raw materials

A

CHON and triglycerides synthesis, glycogenesis

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10
Q

example of catabolic - breakdown of larger molecules

A

glycolysis, beta oxidation, glycogenolysis

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11
Q

example of amphibolic

A

citric acid cycle

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12
Q

second messenger of insulin and growth factor

A

tyrosine kinase

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13
Q

2nd msgr that activate CHON kinase C and release intracellilar Ca

A

DAG, inositol triphosphate

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14
Q

Transporter all tissues esp red cell brain

A

GLUT 1

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15
Q

transporter for brain

A

GLUT 1 & 3

16
Q

differentiate 2types of glycolysis

A

aerobic - cells with mitochondria and adequate O2 supply,
PYRUVATE, ex. resting muscle
anaerobic - cells without ….
LACTATE ex. rbc, exercising muscle cramps…

17
Q

rate limiting reaction of glycolytic pathway, pace setting enzyme of glycolysis

A

PFK 1

18
Q

fxn of PKF 2?

A

converts F-6-P to F-2,6-BP, activate to enhance PFK 1

19
Q

is the second most common cause ( after glucose 6 phospate DH deficiency) of enzyme def. related chronic HEMOLYTIC ANEMIA
most common enzyme defect in glycolysis

A

Pyruvate kinase deficiency

20
Q

how many net mol. of ATP can be produced from 1 glucose mol. via substrate - level phosphorylation?

A

2 ATP molecules

21
Q

in what part of the cell can you find the electron transport chain

A

inner mitochondrial mem.

22
Q

activator of PFK 1?

inhibitor?

A

activator: F 2,6 BP & AMP
inhibitor: ATP & citrate

23
Q

found in RBC where phosphoglycerate kinase is bypassed,
it is also binds to hgb to let go oxygen. “kabit” to let go oxygen.. higher altitude environment so oxygen will release..

A

2,3 Bisphosphoglycerate

24
Q

inhibits pyruvate DH by binding to lipoic acid

A

arsenic poisoning

25
Q

most common biochemical cause of congenital lactic acidosis
x-linked dominant condition, inc. lactate, dec acetyl CoA.
tx. ketogenic diet

A

Pyruvate dehydrogenase deficiency

26
Q

co enzyme of conversion of pyruvate to acetyl CoA?

A

lipoic acid, NAD, FAD, Thiamine pyrophosphate, Coenzyme A - pantothenic acid