Carbapenems Flashcards
Imipenem - cilastatin
Names of carbapenems
Imipenem - cilastatin Meropenem
how do carbapenems work
they destroy bacteria cell wall
How are they used
the broad antibacterial spectrum is effective for serious infections
Resistence develops from using imipenem alone to treat pseudomonas aeruginosa infections
this pathogen requires a combination of antipseudomonal medications
allergy , hypersensitivity
monitor for indications of allergic reactions to PCN and cephalosporins
monitor for
suprainfection, gastrointestional upset
what should you monitor for a pt with siezures and siezure medication
Imipenem - cilastatin can reduce blood levels of Valporic acid and breakthrough siezures are possible
Other med that works on bacteria cell wall -
Vancomycin for po iv use , aztreonam , a monobactam, fosfomycin
Vancomycin
use for PO IV use
ototoxicity
with vancomycin - monitor levels, rare and reversible
Vancomycin is used to treat infections with.
MRSA
What is the infusion reaction seen with Vancomycin
Redman Syndrome : Rashes , Flushing Tachycardia and hypotension administer slowly over 60 min
Im IV injection site reaction
Thrombophlebitis - monitor the infusion site for redness , swelling and inflammation
Renal toxicity
Monitor trough levels , for trough check blood before medication administration - peak 30 min - 1 hr after giving medication
What food products should a pt notice of possible contraindication to use of vancomycin
Corn products , an allergy to corn products and previous allergy to vancomycin are contraindications
