Carbamazepine Flashcards
1
Q
Class of carbamazepine
A
Anti-convulsants
2
Q
How does carbamazepine reduce excitability
A
- block v-gated Na channels —> slow recovery
- open K channels
- ++ GABA release
3
Q
Indications for carbamazepine
A
- epilepsy
- trigeminal neuralgia
- bipolar prophylaxis
4
Q
Contraindication for carbamazepine
A
- AV conduction abnormalities
- BM disease
- liver disease
5
Q
Side effects of carbamazepine
A
- cardiac
- BM failure
- Stevens-Johnson syndrome