Car 6 - Edema And Shock Flashcards
What are the four starling forces affecting capillaries?
Pc: Capillary pressure (the hydrostatic pressure of blood in the capillary; pushes fluid out of the cap). Pi: Interstitial pressure (pushes fluid into the cap). Pi-c: Colloid osmotic pressure of the plasma inside the cap (absorbs fluid into the cap.) Pi-i: Colloid of the interstitium (absorbs fluid into the intersti).
What is Filtration constant (Kf)?
Measure of capillary permeability.
What things will cause increase in capillary hydrostatic pressure?
CHF (^ central venous pressure). Venous thrombosis (locally). Compression of veins. Na and H2O retention.
What three things can ^ capillary permeability?
Infections and septic shock. Toxins. Burns.
What things \/ plasma colloid osmotic pressure?
Nephrotic syndrome. Liver disease (no protein making). Protein malnutrition. Protein-losing enteropathy.
What things ^ interstitial colloid osmotic pressure?
Lymphathic obstruction.
What is the difference b/w pitting edema vs Non-pitting edema?
Pitting edema: excess amount of fluid in absence of additional colloid (a gravity phenom, leaves indentation mark after pressing in). Non-pitting edema: Colloid in interstitial fluid (doesn’t leave indentation after pressing).
What is the difference b/w Transudate vs Exudate?
Transudate is Protein-poor edema fluid. Exudate is Protein-rich edema fluid [exudate is Extra stuff].
What two things would cause transudate?
^ capillary pressure. \/ plasma protein.
What would cause exudate?
^ capillary permeability.
What would the SVR (systemic vascular resistance), CO (cardiac output) and Tx be for Hypovolemic shock?
SVR: ^. CO:\/. Tx: IV fluids/blood.
What would the SVR, CO and Tx be for Cardiogenic shock?
SVR:^. CO: \/. Tx: Dobutamine.
What would the SVR, CO and Tx be for sepsis/anaphylaxis?
SVR: \/. CO:^. Tx: Antibiotics, IV fluids, Norepinephrine.
What would the SVR, CO and Tx be for Neurogenic shock?
SVR: \/. CO: \/. Tx: IV fluids. If spinal cord injury: usually high dose steroids to reduce core edema.
What would be seven causes of Cadiogenic shock?
MI. Pulmonary embolism. CHF. Arrhytmias. Cardiac tamponade. Tension pneumothorax. Cardiac contusion.