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ross hypothermia > CAPA ABX > Flashcards

CAPA ABX Flashcards

1
Q

PenG admin

A

IV or IM

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2
Q

Pen VK admin

A

PO

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3
Q

Benzthine penicillin admin

A

long acting IM (syphillus)

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4
Q

Common treatments for natural penicillinss

A

strep pharngitis, cellulitis

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5
Q

Aminopenicillins (2 examples)

A

ampicillin, amoxicillin

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6
Q

Ampicillin admin

A

IV

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7
Q

Common treatment for aminopenicillins

A

pharyngitits, sinusitis, otitis media, endocarditis prophalaxsis, lyme dz (for patients under 8)

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8
Q

Antistaph penicillins do/do not have MRSA coverage

A

DO NOT

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9
Q

Antistaph penicillins examples (2)

A

nafcillin (IV), dicloxacillin

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10
Q

Antistaph penicillins treatments

A

skin and soft tissue with suspected staph, but works well against strep as well

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11
Q

Augmented penicillins examples

A

augmentin, ampicllin/sulbactam (unasyn) (IV)

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12
Q

Coverage of aminopenicillins

A

streps, enterococci, boriellia bordorfi, listeria

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13
Q

Coverage of augmented penicillins

A

streps, enterococci, bergdorfi, lsiteria+ pastuerlla, morxella, Hflu, anaerobes**

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14
Q

treatment for augmented aminopencillins

A

dog bites, human bites, otitist media, sinusistis, acute exacerbation of chronic bronch, dental infections, skin and soft tissue

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15
Q

Augmented extended spectrum example…and added covereage

A

piptazo, all the above + PSEUDOMONAS

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16
Q

MOA of penicillins

A

stops cell wall syntesis by binding penicillin binding protein

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17
Q

Penicillin MOR

A

lactamases and PBP alteration

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18
Q

Peniciliins are ________ processed

A

renally

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19
Q

Clavulanate is associated with __________(adr)

A

diarrhea

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20
Q

Ceaphalosporins (1 gen) has great ___________ but poor _________ coverage

A

gram + (EXCEPT MRSA), gram-

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21
Q

examples of 1st gen cephalosporins

A

cefazolin (ancef IV) or cephalexin (Keflex PO)

22
Q

What doesn’t 1st gen cephalosporin cover?

23
Q

Common treatment indiciations for 1st gen cephalosporins

A

skin and soft tissue, strep pharyngitis, preof prophalzais (cefazolin), uncomplicated cyctisit

24
Q

2nd gen cephalosporins examples

A

cefuroxime (ceftin)

25
Q

2nd gen coverage

A

covers same as 1st, +strep pneumo, mcat, hflu

26
Q

1st gen ceph coverage

A

strep pyogenes, MSSA, some gram - E coli, klebsiella, proteus

27
Q

2nd generation cephalosporins exampel

A

cefuroxime (ceftin PO)

28
Q

3rd generation cephalosporins examples

A

Ceftriazone (IV IM), cefdini (omnicef PO)

29
Q

3rd gen ceph coverage

A

gram - with some gram +, NOT enteroccosu or MRSA

30
Q

4th gen name and coverage

A

cefepime (IV) most gram - rods, +PSEUDOMONAS***

31
Q

Next gen cephalosporins name and coverage

A

very broad gram - and gram + coverage, MRSA coverage**

32
Q

penem general coverage

A

broad, excellent gram -, includes pseudomonas** (except ertapenem)

33
Q

Carbapenems are usually used for __________

A

more resistant bacteria such as ESBL and pseudomonas

34
Q

ADRs for carbapenems

A

seizures (especially imipnenm) and nephrotoxicity

35
Q

Tetracyclines does or do not cover MRSA

36
Q

MOA of tetercyclines

A

protein synthesis inhibition at 30S bacterial ribosome

37
Q

MOR of tetracyclines

A

efflux pump

38
Q

ADRs for tetracyclines

A

photosensitivity, contrainidicated in pregnancy

39
Q

examples of tetracyclines

A

mino, tetra, doxy

40
Q

Macrolides examples

A

ACE, Azitrho (PO or IV), claritho (PO), erythromycin (PO or IV)

41
Q

Macrolide coverage

A

strep pneumo, strep pyogenes, mcat,, Hflu, ***chlamydia, mycoplasm, hpylori, bordetella pertusis

42
Q

MOA of macrolides

A

protein synthesis inhibition at 50S ribosome

43
Q

MOR of macrolides ribosolmal changes and efflux pump

44
Q

Safety concerns with macrolides

A

Clrithro is a CYPA4 inhibitor, monitor warfarin. QT prolonations (azithro)

45
Q

ADR to erythromycin

A

nausea/vomiting/diarrhea

46
Q

Special treatment for macrolides

A

whooping cough**

47
Q

Lincosamides examples

A

clindamycin (PO, IV)

48
Q

Coverage of lincosamides

A

anaerobes above diaphragm, Staph/strep in PCN allergic patient

49
Q

MOA of lincosamides

A

protein synt inhibition at the 50S ribosome

50
Q

MOR of lincosamides

A

ribosomal modications

51
Q

ADRS of lincosamides

A

Nause/ diarrhea, CDIFF

ross hypothermia (2 decks)

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