CANMAT depression meds Flashcards

1
Q

1st line meds for depression

A

SSRI, SNRI, buproprion, mirtazapine, moclobemide

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2
Q

1st line switch (superiority among 1st line)

A
sertraline 
escitalopram
mitazapine
venlafaxine
duloxetine
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3
Q

1st line add on

A

Li
Olanzapine
Risperidone
Aripiprazole

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4
Q

2nd line antidepressants

A
clomipramine
amitryptiline
Other TCAs
Selegeline TD patch
Trazodone
seroquel
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5
Q

2nd line add on

A

T3
Quetipaine
Buproprion
Mirtazapine

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6
Q

3rd line antidepressants

A

phenelzine

tranylcypromine

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7
Q

3rd line add on

A

ziprazidone
buspyrone
modafinil
stimulants

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8
Q

worst sexual SE among antidepressants

A
sertraline
fluoxetine
fluvoxamine
paroxetine
>30%
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9
Q

least sexual SE among antidepressants

A
buproprion
mirtazapine
moclobemide
selegeline
<10%
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10
Q

worst interactions (antidepressants)

A
fluvoxamine
fluoxetine
paroxitine
sertraline
moclobeminde
selegeline
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11
Q

least interactions (antidepressants)

A
citalopram
escitalopram
venlafaxine
desvenlafaxine
mirtazapine
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12
Q

1st line antidepressants in pregnant women

A

SSRIs except paroxetine

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13
Q

1st line antidepressants in nursing mothers

A
sertraline,
 paroxetine, 
citalopram 
nortryptiline
(not fluoxetine)
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14
Q

1st line antidepressants in youth

..and discuss a bit

A
fluoxetine
citalopram
Though FDA is prozac and escitalopram
other SSRIs except paroxetine 2nd line
venlafaxine worse SE and SI
Combine with CBT for best results
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15
Q

level 1 evidence for prevention in seasonal ?

A

wellbutrin

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