Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

CANMAT bipolar > CANMAT bipolar I and II > Flashcards

CANMAT bipolar I and II Flashcards

1
Q

1st line monotherapy for acute bipolar I mania

A 
monotherapy:
Li
Epival
Almost Any AA:
ROQA ZAP
 (olanzapine, risperidone, quetiapine, aripiprazole, asenapine, paliperidone ER, ziprazidone)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

1st line combo therapy for acute bipolar I mania

A 
Li OR epival plus:
ROQAA (you rock when you're 1st line maniac)
risperidal
olanzapine
Quetiapine
Aripiprazole
Asenapine
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

2nd line monotherapy for acute bipolar 1 mania

A

HEC (hectagons may have many sides, but 2nd line BD1 mania is short and sweet)
Haldol
ECT
Carbamazepine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

2nd line combo for acute bipolar 1 mania

A

Li+ Epival

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

3rd line monotherapy for acute bipolar 1 mania

A

non-comprehensive list: COT
clozapine
oxcarbazepine
tamoxifen (mono or adj)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

not recommended for acute bipolar 1 mania

A

mono: Vera and Gaba were tied on top of the lama
verapamil gabapentin, tiagabine, topiramate, lamotrigine
combo: risperidoe or olanzapine with carbamazepine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

all 1st line for acute bipolar I mania

A 
Monotherapy:
Li
Epival
Almost any
 ROQA ZAP
Any AA (olanzapine, risperidone, quetiapine, aripiprazole, asenapine, paliperidone ER, ziprazidone)
Combi therapy:
Li OR epival plus:
ROQAA (you rock when you're 1st line maniac)
risperidal
olanzapine
Quetiapine
Aripiprazole
Asenapine
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

all 2nd line for acute bipolar 1 mania

A 
Mono:
HEC (hectagons may have many sides, but 2nd line BD1 mania is short and sweet)
Haldol
ECT
Carbamazepine

Combi:
Li+ Epival

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

1st line for bipolar I acute depression

A

Mono:
Li
Lamotrigine
Quetiapine

Combi:
Li+epival
Li or epival + SSRI or Buproprion
Olanzapine + SSRI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

2nd line bipolar I acute depression

A

mono:
epival, lurasidone

combi:
Li or epival plus lamotrigine or lurasidone
quetiapine +SSRI
adj modafinil

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

3rd line bipolar I acute depression

A

not comprehensive list:
quetiapine + lamotrigine
Li Plus: MAOI, pramipexole, or carbamazepine
Li or Epival plus: TCA or venlafaxine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

not recommended bipolar I acute depression

A

It’s not recommended to ZAG alone when depressed
Ziprazidone
Aripiprazole
Gabapentin

adj ziprazidone
adj Leveteracetam

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

1st line bipolar I maintenance

A 
Mono: 
Li
epival
lamotrigine
AA: ROQA
not ZAP (zipraz, paliperidone, asenapine) which are there fr acute
comb:
Li or epival plus:
RAQZ (3ashan ti7fath)
Risperdal
Abilify
Quetiapine
ziprazidone

Note :risp is LAI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

2nd line Bipolar 1 maintenace

A

mono: CP
Combo: LiO

CP LELCRO OLEF

Mono:
carbamazepine
Paliperidone ER

Combi:
Li plus: ELCRO= L ELCRO
divalproex
carbamazepine
lamotrigine

risperdal (reg)
olanzapine

Olanzapine plus: LEF= OLEF
Li
Epival
Fluoxetine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

3rd line bipolar I mainitenence

A 
asenapine
adj COT
clozapine
oxcarbazepine 
?
ECT (which is always 3rd line except in bipolar mania acute: 2nd )
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

not recommended Bipolar 1 DO maintenece

A 
Not recommended to play TAG long term
gabapentin
topiramate
antidepressants
adj flupenthixol
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

1st line for acute bipolar II depression

A

Quetiapine

18
Q

2nd line for acute bipolar II depression

A

lamotrigine, Li, divalproex
Li or divalproex or AA plus antidepressant
Li plus divalproex

2nd line BD2=1st L BD1

19
Q

3rd line for acute bipolar II depression

A 
antidepressants alone (as an exception)
quetiapine+ lamotrigine
adj ECT
adj T3
adj NAC
20
Q

Not recommended for acute bipolar II depression

A

antidepressant monotherapy (but 3rd line)

21
Q

1st line bipolar II maintenance

A

1st line here is only mono

quetiapine, lamotrigine, Li

22
Q

2nd line bipolar II maintenance

A

Similar to 2nd line acute bipolar II, but mostly combo
Only epival is mono, so:

divalproex

Desperation with these patients. anything goes:
any combo of 2 mood stabilizers, or of Li, epival, AA
Li or divalproex or mood stabilizer or AA plus antidepressant

specifically though encompassed above.
adj quetiapine
adj lamotrigine

23
Q

Not recommended for maintenence bipolar II depression

A

gabapentin as ususual

24
Q

3rd line bipolar II maintenance

A

ECT, carbamazepine, oxcarbazepine, AA, fluoxetine

25
Q

rapid cycling RF

A 
Factors favoring its occurrence include:
• female gender;
• borderline hypothyroidism
• menopause;
• temporal lobe dysrhythmias
• BAD-II
• substance abuse
26
Q

what is gabapentin not recommended for?

A

acute BD1 depression
acute BD 1 mania
BD1 maintenance
BD 2 maintenance

27
Q

2005 mixed states

A

epival
carbamaz (it’sa predictor of response to carbamaz)
oxcarbaz
olanzapine
ECT
combination likely needed
2013 added that asenapine decreased depressive sx, and olanzapine decreased both depressive and manic sx
riperidone andziprazidone also mentioned.

28
Q

2005 rapid cycling

A

epival plus Li
epival
olanzapine (and AA in general)
ECT
combination Li or carbamaz with something better than either alone
(rapid cycling is a predictor of non response to carbamaz)

29
Q 
2013 prevalence of
 BD1
BD2
NOS
sex ratio
A

0.6%
0.4%
1.5%
all together makes 2.5 %
equal

30
Q

emergency tx of mania

A

oral : ROS
IM:OAZ, Haldol plus ativan
not benzo alone

31
Q

RF for recurrence in rapid cyclers

A

SUD
early verbal abuse
female
late onset depressive sx

32
Q

rate of rapid cycling
rate of mixed episodes
rate of psychotic sx

A

20%, STEP BD: 5%
70% in BD2, 65% in BD I, STEP BD 15%
30-50%

33
Q

manic switch with antidperessants

A

more in bipolar 1
TCA and effexor: 13-38%
vs Wellbutrin and SSRI 3-11%
76% with subsances

34
Q

cognitive deficits in BD 1 and 2

A

same but 2 have better memory and semantics and improve with donepezil

35
Q

CVD mortality more in 1 or 2?

A

2 is double

36
Q

migraines?

A

32% of BD 2, 20% of1

37
Q 
Rates of CB:
obesity:
DM
migraines
SUD
nicotene
anxiety
A 
Obesity  42%
DM: 27%
migraines: 25%
SUD: 70%
nicotine: 25 %(? 32 in step BD)
anxiety: 50% (? 32 in step BD)
ADHD 18% (? 10% in step BD)
38
Q 
# 1 CB 
in geri
adults
adolescents
children
A

neuro dis
SUD (if not a choice, anxiety)
ODD (90%, vs ADHD is 85%)
ADHD

39
Q

FDA approved AA for bipolar in adolescents

A

ROQA

40
Q

geri bipolar chch

A

more:
rapid cycling
mixed
good prognosis

less:
suicide attempts
severe manias
psychotic sx

same depressive sx
late onset is over 50

41
Q

predictors of response to AA

A

young age of onset
rapid cycling
no antipsychotics or drugs rior

42
Q

predictors of response to carbamaz

A 
mixed
more manic states
severe mania
no fmily hisory
early onst

non responseif >10 yrs of illness, rapid cycling

CANMAT bipolar (1 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions