Canine Flashcards
What drug shouldn’t you use to tx aggression and why?
Benzodiazepines disinhibit fear-motivated aggression.
Breeds predisposed to compulsive disorders (4).
Doberman
Bull terrier
GSD
Mini schnauzer
When tx compulsive disorders, how long to see response to SSRI’s?
8 weeks
Which signalment will most likely show submissive inappropriate urination?
yougn female dogs
Boxer with syncope and sudden death
Arrhythmogenic RV cardiomyopathy
How do you diagnose ARVC (arrythmogenic RV cardiomyopathy)?
What is considered disease?
When should you treat?
What do you tx with?
24-Holter monitor
Disease = >100 VPCs/day OR runs of 2-3 VPCs OR ventricular tachy
Tx >1000 VPCs/day OR runs of v-tachy OR evidence of R on T
Sotalol or Mexiletine + Atenolol
What is pulsus alternans?
What arrythmia is it assc with?
Two quick normal pulses in a row followed by a pulse deficit
Assc w/ atrial fibrillation
Irregularly irregular rhythm with no p-waves
atrial fibrilation
When should you tx VPCs (4)?
HR >180
Pulse deficits
clinical signs
VPC runs >20s
Sequela to VPCs (3)?
Hypotension
Myocardial ischemia
CHF
Wide and bizarre QRS on ECG is assc with
VPC
How do you tx VPCs in dogs and cats?
Dogs - Lidocaine; once controlled procainamide, quinidine, propanolol
Cats - propanolol only
How do you tx ventricular tachycardia?
Lidocaine.
If no response, then Procainamide or Quinidine
Is ventricular tachycardia a shockable rhythm?
Yes
Absent P-waves, oscillation of baseline, lack of QRS
Ventricular fibrillation
What does the ECG of v-fib look like?
Absent P-waves
Oscillation of baseline
Lack of QRS
Is ventricular fibrillation a shockable rhythm?
Yes
Is ventricular asystole a shockable rhythm?
No
What must you do before shocking a patient you believe is in v-fib?
Check on ECG that it’s NOT VENTRICULAR ASYSTOLE.
What is the MST of a Doberman with DCM?
2 mos after diagnosis
What are 2 breeds assc w/ DCM?
Doberman
Cocker Spaniel
What causes DCM in cocker spaniels?
Taurine deficiency
A big round heart on CXR suggests what?
DCM
How do you tx DCM (3)?
Taurine supplementation
L-carnitine
Omega 3 FAs
How do you tx ventricular asystole?
Low does Epi and/or Vasopressin
Cardiopulmonary arrest is also known as
ventricular asystole
1 congenital heart abn?
PDA
Puppy at first vaccine visit with continuous murmur
PDA
Murmur heard in PDA
“washing machine” murmur
“Washing machine” murmur
“Water hammer” arterial pulse
PDA
CXR - over-vascularization of lungs, ductus bump
PDA
PDA CXR
over-vascularization of lungs
ductus bump
Tx for PDA
ductus ligation IF <2 yo
2 congenital heart abn in dogs?
pulmonic stenosis
Sudden death of a beagle with RV hypertrophy
Pulmonic stenosis
Primary strutural change seen with pulmonic stenosis?
RV concentric hypertrophy
L basilar systolic murmur between 2-4 ICS
pulmonic stenosis
CXR - reverse “D”
pulmonic stenosis
pulmonic stenosis murmur
L basilar systolic murmur between 2-4 ICS
Pulmonic stenosis CXR
reverse “D”
When should you tx pulmonic stenosis?
Only if resulting cardiac changes or blood pressure
Tx for pulmonic stenosis
Diuresis
Salt restriction
Exercise restriction
What condition is a “patch graft” surgery for?
pulmmonic stenosis
Which breeds typically develop mitral valve dysplasia?
GSD, Great Danes
Newfoundland with ascites, syncope, and ejection-type systolic murmur (crescendo-decrescendo).
subaortic stenosis
What is a risk of subaortic stenosis?
infective endocarditis
Murmur for subaortic stenosis?
ejection-type systolic murmur
crescendo-decrescendo
L 2-5 ICS or at thoracic inlet
Tetralogy of Fallot
RV hypetrophy
VSD
overriding aorta
pulmonic stenosis
What CBC change is seen with tetralogy of fallot?
polycythemia d/t hypoxemia
Which breed is assc w/ Tetralogy of Fallot?
Keeshond
What is the definitive Dx for CHF?
Echo
CHF has a juvenile onset in which breed?
Portuguese Water Dog
Breeds assc w/ CHF (3)
Doberman
Great Dane
Boxer
Tx for CHF: acute vs chronic
FOPS: Furosemide, O2, Pimobendan, Sedation
Diuretics
Dilators
Diet - low sodium
What does Quinidine do?
reduce HR, neg chronotrope
Name 2 beta-blockers
Atenolol, Propanolol
What class are Atenolol and Propanolol? What do they do?
beta-blockers
reduce HR
MOA of Diltiazem?
Ca-channel blocker, reduces HR
MOA of Dobutamine?
beta-1 adrenergic agonist
strength contraction
Recently adopted dog w/ interittent cough containing foam and blood.
CXR shows lung patterns, RV enlargement, and enlarged pulmonary arteries.
Dirofilaria immitis
What is caval syndrome?
Cause?
c/s?
Tx?
d/t retrograde migration of Dirofilaria into vena cava
Shock, collapse, hemoglobinuria, respiratory distress, ascites.
FATAL w/o surgical extraction of worms
When testing for HW, a positive Ag SNAP means what?
Diagnostic for adult females
CXR for HW
Enlarged pulmonary arteries
Pulmonary infiltrates
Hilar lymphadenopathy
RV enlargement
3 diagnostics for HW?
Ag SNAP - adult females
Microfilaria test
CXR
CBC/chem changes for HW?
Anemia
thrombocytopenia
eosinophilia
Hyperglobulinemia
Hypoalbuminemia
Tx for HW in cats? Why?
Only PREDNISONE.
Immiticide/adulticide may cause thromoembolism.
Tx HW in dogs?
Doxycycline - reduce Wolbachia
Ivermectin
Melarsomine
Prednisone
Strict exercise restriction
What looks similar to Dirofilaria immitis but is non-pathogenic?
Dipetalonema reconditum
Pulmonary hypertension leads to what heart change?
RV hypertrophy
What is the Cushing’s reflex?
Hypertension with bradycardia to maintain intracranial perfusion
What sBP causes organ damage?
sBP >160 sustained
Drug to Tx systemic hypertension?
Amlodipine
What is Amlodipine used to tx?
hypertension
Which drug is contraindicated in pericardial effusion?
Furosemide - decreases R preload
Nutmeg liver on Nx is assc with
hepatic venous congestion
How do you diagnose pericardial effusion?
Pericardiocentesis
Fluid analysis
What is pulsus paradoxus? Which disease is it assc with?
Weak on inspiration, strong on expiration
Pericardial effusion
What is electrical alternans? Which disease is it assc with?
QRS varying in amplitude
Pericardial effusion
2 ECG abn seen with pericardial effusion?
Pulsus paradoxus
Electrical alternans
A transudate pericardial effusion is assc with which blood abn?
hypoalbuminemiaI
1 cause of CHF in dogs?
MMVD
Murmur w/ MMVD?
Soft systolic progressing to holo plateau
L 506 ICS
“Jet lesions” are assc w/ what cardiac dz?
MMVD, endocardiosis
Congenital dysplastic MMVD is assc with which 2 breeds?
GSD, Great Dane
Which drug is contraindicated in tx MMVD?
Digoxin
Tricuspid valve insufficiency is usually d/t what disease?
MMVD/endocardiosis
Murmur assc w/ TV insufficiency?
Holosystolic R 4th ICS
R Holosystolic murmur 4th ICS
Tall P-wave
RA enlargement, hepatomegaly, ascites
Tricuspid valve insufficiency
Tx tricuspid valve insufficiency
Diuretics
Dilators
Diet
rest
Digoxin
Above what BG will you see glucosuria in dog/cat?
dog > 180
cat > 200
C/s of DM?
PU/PD
PP + wt loss
Chemistry changes w/ DM?
Hyperglycemia >300
Metabolic acidosis
Elv liver enzymes
Hypercholesterolemia
Diet change for dog with DM?
Increase dietary fiber
What disease is hepatocutaneous syndrome assc with?
Diabetes mellitus, FATAL
How does DM differ in c/s from:
EPI
Cushing’s
Hypothyroid
EPI - PP + wt loss, no PU/PD
Cushing’s - PU/PD, PP w/o wt loss
Hypothyroid - wt gain w/o PP
Dog in DKA - first tx?
IVF - Correct acidosis, e’lytes, hyperosmolality
DKA - concurrent diseases (6)
Pancreatitis
UTI
Bacterial infections
Hyperthyroid
Cardiac dz
Cushing’s
BG in DKA?
> 500 g/dl
Dx Cushing’s
- Screen: LDDST
- Differentiate: HDDST
CBC/chem abn in Cushing’s
Stress leukogram
Thrombocytosis
EXTREMELY ELV ALP
Hypercholesterolemia
When Dx Cushing’s, a normal urine cortisol:creatinine means what?
Normal r/o Cushing’s
Tx Cushing’s
Trilostane - PDH
Lysodren
Adrenalectomy
PU/PD, PP, panting
Truncal alopecia, pot belly, calcinosis cutis
Cushing’s
7 yo Standard Poodle that is vomiting, weak, dehydrated, and severely bradycardic.
Addison’s
What should you do first to Tx Addison’s?
Start aggressive IVF to restore vascular volume
Run chemistry panel
3 yo FS Lab with vomiting and ADR for 3 days. She’s depressed, dehydrated, and hypoperfused.
She’s initially responsive to IVF and Abx.
Bloodwork shows azotemia, hyponatremia, hyperkalemia.
Addison’s
What are the 4 tip-offs of Addisons?
Bradycardia
Severe dehydration
Low Na:K
NO stress leukogram
Why does Addison’s cause hypovolemic shock?
Low aldosterone causes hyponatremia, hyperkalemia –> PU/PD –> dehydration –> shock
What is medullary washout?
Chronic severe PU/PD results in severe depletion of solutes, thus imparing reabs of Na, Cl, and urea.
Therefore, no urine concentration will occur despite endogenous antidiuretics and intact receptors.
How to Dx Addison’s?
ACTH stim test
LOW resting cortisol +
Blunted response to Cosynotropin
ECG - hyperkalemia
Bradycardia
Tall T-wave
Absent P-wave
prolonged P-R
wide QRS
Older Golden retriever that’s lethargic, has recently gained weight but has a normal appetite. She has symmetric alopecia, neuro signs, and a tragic face.
Hypothyroidism
4 yo Doberman with symmetric alopecia, lethargy, and gaining weight but normal appetite.
Bloodwork shows nnn anemia and hypercholesterolemia.
Hypothyroidism
Bloodwork abn with Hypothyroidism
nnn anemia
hyperlipidemia
hypercholesterolemia
What is the primary cause of hypothyroidism?
lymphocytic thyroiditis
What is myxedema coma?
Tragic face = droopy eyes, thickened facial skin
Coma, hypothermia, bradycardia
How to Dx Hypothyroidism?
freeT4 by ED - confirms, r/o euthyroid
TSH stim - gold standard but expensive
How to tx Hypothyroid?
Levothyroxin
Bloodwork abn with Coronavirus?
Anemia
Neutrophilia
lymphopenia
elv ALP, elv ALT
What is tertiary dentin?
Get from aggressive chewing, stains easily, turns brown