Candidiasis Flashcards

1
Q

Candidiasis is infection with ______ caused by _________

A

Infection with Candida species, caused by an overgrowth of the organisms often present in small amounts in the genital tract

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the usual organism that causes candidiasis?

A

Candida albicans

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Is candidiasis considered to be an STI?

A

No

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What causes candidiasis?

A

Often no clear cause but some risk factors have been identified

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Risk factors for candidiasis include…

A

Abx use (within past 3m)
Poorly controlled diabetes
Increase in oestrogen (exogenous or endogenous) including pregnancy, MHT and possibly COC
Skin conditions e.g. eczema or dermatitis
Immunosuppression

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Candidiasis may cause _________ in males, especially if __________

A

May cause balanitis, especially if uncircumcised

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Presentation of vulvovaginal candidiasis infection

A

White ‘curd like’ vaginal discharge
Genital or vulval itch, discomfort
Superficial dyspareunia
External dysuria
Excoriation, erythema, fissures, swelling

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Is discharge always abnormal with candidiasis?

A

No, can appear normal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Presentation of penile candidiasis infection

A

Red rash on genitals, especially under foreskin (may or may not be itchy)
Swelling of foreskin if severe
Fissures
Superficial erosions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

How common is candidiasis in women?

A

~75% women will experience at least one lifetime episode

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

_____ % of women will have recurrent candidiasis

A

<5%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Recurrent candidiasis defined as…

A

4 or more symptomatic episodes within 12 months

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Indications for testing for candidiasis

A

Vaginal discharge
Vaginal odour or itch
Genital discomfort
Superficial dyspareunia
Genital rash, erosions or fissures

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Should you test asymptomatic people for candidiasis?

A

Routine screening in asymptomatic people is not recommended

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Why is examination recommended for candidiasis?

A

Exam is recommended for thorough assessment as symptoms are non-specific and may be due to other conditions such as dermatitis or genital herpes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What can you do if examination is declined?

A

Self-collected swabs can be done if exam is declined, but this is not recommended

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Should you also check for STIs?

A

STIs symptoms are similar to those of candidiasis. Unless STIs have been excluded, testing should occur as part of a full sexual health check

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Recurrent candidiasis should be confirmed by ___________ before considering suppressive therapy

A

Culture or microscopy on at least 2 occasions

19
Q

Recommended test for vulvovaginal candidiasis

A

High vaginal swab for Candida and BV

20
Q

________ is another common cause of unusual vaginal discharge

A

BV

21
Q

Other tests to consider

A

Vulvovaginal NAAT swab for chlamydia, gonorrhoea and trichomoniasis
HIV and syphilis serology if STI testing indicated

22
Q

Recommended tests for penile infection

A

Usually diagnosed based on signs and symptoms but can do culture swab for yeast

23
Q

People with confirmed recurrent candida balanitis should be screened for ________

A

Diabetes

24
Q

People with recurrent candida balanitis should discuss…

A

Status of their sexual partner(s) should be discussed (often occurs in the context of untreated recurrent vulvovaginal candidiasis in the partner)

25
Q

Should you treat asymptomatic people?

A

No
Only treat symptomatic people

26
Q

What’s more effective - oral or topical treatments?

A

Topical and oral azoles have a similar efficacy

27
Q

Although not specifically recognised as risk factors people with recurrent candidiasis may benefit from avoidance of…

A

Perfumed products and tight clothing that promotes excessive sweating e.g. wetsuits, synthetic underwear

28
Q

If breakthrough symptoms on suppressive therapy occur…

A

Confirm ongoing candida before changing treatment regimen.
Request culture swab for speciation and sensitivities, and write ‘breakthrough symptoms while on suppressive therapy’ on the request form

29
Q

Recommended treatment for acute vulvovaginal candidiasis

A

Clotrimazole 2% vaginal cream, one vaginal applicator every night for 3 days
OR
Fluconazole 150 mg orally, as a single dose

30
Q

Alternative treatment for acute vulvovaginal candidiasis

A

Nystatin vaginal cream, one applicator 1-2 times daily for 2 weeks
OR
Miconazole 2% vaginal cream, one vaginal applicator every night for 7 days

31
Q

Recommended treatment for acute penile candidiasis

A

Clotrimazole 1% topical cream twice daily for 5-7 days

32
Q

Alternative treatment for acute penile candidiasis

A

Miconazole 2% topical cream twice daily for 5-7 days

33
Q

Recommended treatment for recurrent vulvovaginal candidiasis

A

Induction with fluconazole 150 mg orally, every 72 hours for 3 doses, followed by maintenance with fluconazole 150 mg orally, weekly for 6 months

34
Q

Alternative treatment for recurrent vulvovaginal candidiasis

A

Clotrimazole 2% vaginal cream one vaginal applicator every night for 3 days. Repeat every month for 6 months

35
Q

What should you do if recurrent vulvovaginal candidiasis due to non-albicans species or resistant C. albicans

A

Seek specialist advice

36
Q

General advice for management/vulval care

A

Avoid local irritants e.g. soaps, bath oils, body washes, bubble baths, spermicides, vaginal lubricants, vaginal hygiene products
Soap substitute for washing e.g. Sorbolene, Cetaphil, QV

37
Q

Important advice in terms of contraception while on treatment for candidiasis

A

Latex condoms, diaphragms and cervical caps can be damaged by antifungal vaginal creams

38
Q

Should you treat sexual partners?

A

Sexual partners only require treatment if symptomatic

39
Q

Does diet/probiotics have an effect on candidiasis?

A

No strong evidence that specific diets or the use of probiotics influence the recurrence of candidiasis

40
Q

Treatment in someone who is breastfeeding

A

Same as above

41
Q

Treatment in someone who is pregnant

A

Fluconazole contraindicated, may need longer course of topical treatment

42
Q

Is contact tracing required?

A

No

43
Q

Is follow up required?

A

No (unless sx persist or recur)
No test of cure required

44
Q

Referral to or discussion with a sexual health specialist is recommended for…

A

Persistent or recurrent candidiasis
Failure to respond to above treatment
Complicated clinical situations for further management