Candida (Boyington)

Question 1

5 most common candida species that cause human infection.

Answer 1

albicans. glabrata. tropicalis. parapsilosis. krusek

Question 2

risk factors for the development of candida infections (8)

Answer 2

HIV/immunodeficiency. neutropenia. prematurity (infants). treatment with steroids/chemo/for diabetes. neutrophil defects. antibiotic treatment. indwelling lines, parental nutrition, burn patients. GI surgery.

Question 3

clinical manifestations of candida infections:normal host?

Answer 3

thrush, vaginitis, diaper rash

Question 4

clinical manifestations of candida infections in immuncompromised

Answer 4

thrush, esophageal candidasis. endopthalmitis. endocarditis. UTI. hepatosplenic abcess. peritonitis. meningitis.

Question 5

candidemia is __? so?

Answer 5

life trheatening: so always treat, look for source.

Question 6

candida: always treat?

Answer 6

all positive blood cultures, look for source and remove all lines

Question 7

three antifungals that can treat candida

Answer 7

IV fluconazole for clinically stable. caspofungin for unstable. amphotericin B for either

Question 8

dermaphytosis: what?

Answer 8

superficial fungal infection that invades stratum corneum aka outer layer of skin, as well as other keratinized tissues derived from epidermis

Question 9

dermatophyte: nomenclature

Answer 9

tinea + name of body part

Question 10

dermatophytosis treatment

Answer 10

azole antifungals topically if mild. oral itraconazole, fluconazole, terbinafine

Question 11

clinical features of dermatophytoses

Answer 11

annular aka circular scaling patch with a raised edge that is inflamed. usually centre less inflamed than edge.