Cancers Flashcards
1
Q
What % of cancer syndromes are sporadic?
A
75-85%
2
Q
What % of cancers are familial?
A
10-20%
3
Q
What % of cancers are hereditary?
A
5-10%
4
Q
How are familial cancers inherited?
A
Dominantly inherited (altered allele inherited and in all body cells)
2nd normal allele of gene pair becomes inactivated in somatic cell
5
Q
What do familial cancers lead to?
A
Loss of control of growth and unchecked cell proliferation
6
Q
How are sporadic cancers inherited?
A
Dominantly inherited familial censer syndromes
Both alleles of gene become inactivated in a particular somatic cell
7
Q
What do sporadic cancers lead to?
A
Loss of control of growth and unchecked cell proliferation
8
Q
What do sporadic cancers lead to?
A
Loss of control of growth and unchecked cell proliferation
