Cancer Therapies Flashcards

1
Q

Targeting HER2

A

Transtuzumab

Pertuzumab

Lapatinib

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2
Q

Targeting EGFR

A

Cetuximab

Panitumab

Erlotinib

Gefitinib

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3
Q

Targeting B-Raf V600E

A

Vemurafenib

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4
Q

Inhibit VEGF signalling

A

Aflibercept

Sorafenib
Sunitinib

Bevacuzimab

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5
Q

PARP inhibtors

A

Olaprib

Nirparib

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6
Q

Novel therapies

A

Cytokines
Immunomodulators
Monoclonal antibodies

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7
Q

Cytokines

A

Interleukin 2

Interfeuron alpha

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8
Q

Immunomodulators

A

Thalidomide

Lenalidomide

Pomalidomide

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9
Q

Checkpoint blockade methods

A

CTL4 inhibition

PD1 and PDL1 indibition

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10
Q

Checkpoint blockade (CTL4-A inhibitor)

A

Ipilumumab

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11
Q

Checkpoint blockade (PD1 and PD-L1)

A

Pembrolizumab

Nivolumab

Atezolizumab

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12
Q

Protosome inhibitors

A

Bortezomib

Carfilzomib

Ixazomib

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12
Q

Targeted therapies

A
Proteosome inhibitors
Protein kinase inhibitors
Hedgehog pathway inhibiors
VEGF inhibitor
PARP inhibitors
BCl2 inhibitors
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14
Q

Protein kinase inhibitor

A

Imatanib

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15
Q

Hedgehog pathway inhibitor

A

Vismodegib

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16
Q

Bcl2 inhibitor

A

Venetoclax