Cancer staging and every random thing i can think of Flashcards
esophageal 1 - 4
critical = 3 vs 4
1 vs 2 endoscopic dx
T3 = adventitia
T 4 = invasion in to adjacent structures
T4a resectable (pleura, pericardium diphragm)
T4b NOT (trachea, aorta)
Rectal
Only really need T2
T3 into perirectal fat
T3 = pre-op chemo and RT
Renal
1 < 7cm
2 > 7cm
3 a Renal vein
3 b IVC below
3 c IVC above diaphragm
4 outside gerota or ipsi adrenal
Bladder
T2 muscularis propia
T3 perivesicular (outside bladder)
T4 a prostate uterus vagina
T4 b pelvic sidewall or abdominal wall
Endometrial
Stage 1 vs 2
cervical stroma invasion (don’t see normal cervical mucosal enhancement)
pre op RT and radiacal hyst
cervical cancer
IIa vs IIb
IIa beyond cervix, no parametrial
IIb = parametrial invasion (or lower 1/3 vagine) = chemo/RT
Prostate
2 vs 3
extracapsular extension
lung
unresectable =
unresesctable = Stage 3B (N3 or T4)
3B = supraclavicular, scalene, contra med/hilar (N3)
Same lung, diff lobe = T4
Malig pleural effusion = 3B
3B = unresectable
Diff lung = M1a
Skin doses
Early transient erythema
2Gy
Skin doses
Temporary epilation
3Gy
Skin doses
Main erythema (chronic)
6Gy
Skin doses
permanent hair loss
7Gy
Skin doses
Telangiectasia
10gy
Skin doses
Dry desquamation
13 Gy
Skin doses
Moist
18Gy
Skin doses
Secondary ulceration
24 Gy
Major spill
Tc99
100 mCi
Major spill
Tl 201
100
Major spill
In 111
10 mCi
Major spill
Ga 67
10 mCi
I 131
1 mCi
General public
annual limit
100 mrem
Unrestricted area
2mrem (.02mSv per hour) < 1mSv/7 days
Restricted area
anywhere receiving greater than 2 mrem per hour
Radiation area
> 5 mrem (.05 mSv) in one hour at 30cm
High radiation area
> 100 mrem (1mSv) in 1 hour at 30 cm
Very high radiation
500 rads (5 gray) in one hour at 1 meter
Occupational workers
Lens
150 mSv per year (0.15 Sv, 15 rem)
Occupational workers
Radiation worker
50 mSv/year (5 rem, .05 Sv)
Workers
extremity, individual organ or tissue
500 mSv/year (50 rem, 0.5 Sv)
Public exposure
Infrequent
Continuous
5 mSv/year
1 mSv/year
Embryo/fetus via mother
5 mSv for pregnancy (.005 Sv, .5 rem)
Public exposure
controlled areas
50 mSv/year
Public exposure
uncontrolled areas
5 mSv/year
Genetically significant dose
0.25 mSv
Background US per year
3 mSv
White 1
no special handling
surface <0.5 mrem/hr
1 meter 0
Yellow 2
surface 50 mrem/hr
1 meter <1 mrem/hr
Yellow 3
surface < 200mrem/hr
1 meter < 10 mrem/hr
I 123
Low
159
13 hours
Xe 133
Low
81
125 hours (30 seconds)
Thallium 201
Low
135
167
73 hours
use daughter Hg x rays
I 111
Medium
173
247
67 hours
Gallium
93
184
300
393
78 hours
I 131
365
8 days
F 18
511
110 minutes
Strontium 89
50 days
14 days in bone
Samarium 153
46 hours
Y 90
64 hours
Radium 223
11.4 days
Radionuclide purity
how much moly
Dose calibrator
.15 micro per 1 milli
Chemical purity
How much Al
pH paper
<10 micrograms per 1 ml
Radiochemical purity
Free Tc
Thin layer chrom
nodal SCC neck
N1 < 3 cm
N2 (abc) 3-6 cm
N3 > 6cm
DOSE CALIBRATOR QC
Constancy
Daily
DOSE CALIBRATOR QC
Linearity
Quarterly
DOSE CALIBRATOR QC
Accuracy
Annually
DOSE CALIBRATOR QC
Geometry
Install/repair
1 mCi = ? Bq
1 mCi = 37 MBq
Packages
attended to when?
within 3 hours or right away if they came overnight
/After making sure box not busted?
Survey and wipe
Wipe exceeds yellow 3?
notify carrier and NRC within 24 hours
Recordable vs Reportable
Report wrong patient, route, radiopharmaceutical, or >20% prescribed IF it exceeds occupational limit
5 rem whole body (0.05 Sv) 50 mSv
50 rem body part or skin (0.5 Sv) 500 mSv
Reportable = Call NRC or state within 24 hours, followed by written report
Call MD and patient
Major spill
I 123
10 mCi
Record keeping
3 year records of
Each radionuclide admin
all receipt, storage and disposal
Record of all surveys and calibrations
Record keeping
5 years
actions and management relative to radiation protection program
Permanent record
Duties, authorities and responsibilities of RSO
PPV 1 benchmark
4.4%
0,3,4,5
PPV 2
biopsy recommended
4 or 5
25.4%
PPV 3
31%
PBR
Target recall rate
5-7%
Cancers per 1000 screened
3-8
Mammo
Processor QC
Daily
Mammo
Darkroom cleanliness
Daily
Mammo
viewbox conditions
weekly
Mammo
Phantom eval
Weekly
Mammo
repeat analysis
Quarterly
mammo
Compression test
SEMI annually
Mammo
darkroom fog
semi - annually
Mammo
screen film contrast
semi - annually
How often certified for MQSA
by who
FDA
q 3 years
To have honor of reading mamms?
3 months
240 during a 6 month period in last 2 years
ir sentinel event
15 Gy to single field
Male temporary
.15-2.5 Gy
male permanent
5 Gy
female 12 y
10Gy
Female 45y
2Gy
Female no age
ballpark 6 Gy
ARS
BM
>2Gy
1-6 week latent
ARS
GI
>8 Gy
5-7 day latent
dead in 2 weeks
ARS
CNS
20Gy
4-6 hours latent
3 days dead
Administered activities and critical organs
Gallium scan
6-10 mCi
Colon
Administered activities and critical organs
Bone scan
25 mCi
bladder
Administered activities and critical organs
cysto (sulfur colloid Tc99)
1 mCi
bladder
Administered activities and critical organs
uptake and scan
5 MICRO I 131
10-20 MICRO I 123
Thyroid cancer I 131 doses
100 thyroid
150 nodes
200 distal
Critical organs
I 131 MIBG
Liver
Critical organs
Renal cortex
thallium
DMSA
Critical organs
PO sulfur colloid
Proximal colon
Critical organs
sestamibi
proximal colon
Critical organs
bladder
MAG 3
MDP
Critical organs
Gallium
DISTAL colon
Critical organs
spleen
Octreotide
Damaged RBC’s
In-WBC’s
Critical organs
pertech
Colon
estomago
I 123 administered activity
0.5 mCi
1 mCi = ? Bq
37 MBq
Administered activity
bleeding scan
Tc 99 RBC’s
20-25 mCi
Administered activity
fdg
10-20 mCi
Administered activity
I 131 MIBG
1-2 mCi
Administered activity
I 123 MIBG
10 mCi
Administered activity
Tl 201
2-4 mCi
Administered activity
resting sestimibi cardiac
7-13 mCi
Administered activity
Sestamibi cardiac total
20-40 mCi
Premed protocols
Pred
50mg PO PRED
13, 7 and 1 hours before
50 Benadryl 1 hr before
Premed protocols
methylpred
32 mg methylpred PO
12 and 2 hours before
50 benadryl
Premed protocols
rapid
200 mg hydrocortisone IV q4 until exam
50 ben 1 hr prior
Graves amount
10 mCi
MNG amount
30 mCi
Eovist
proper name
excretion
other biliary guy
Gadoxetate
ionic linear
50% bile, 20 mins
Gadobenate, multihance, 5% bile, 2-3 hours
octreoscan administered activity
6 mCi
I 111 administered activity
0.5 mCi
Tl administered activity
(per oates)
3 mCi
administered activity
I 123 Na iodide
.5 mCi
Gd
macro vs linear
ionic non ionic
macro more stable than linear
of the linear, ionic more stable than nonionic
Gadavist
other macros
Macro, non-ionic
Gadobutrol
teriffic ‘ter’s
Gadoteridol - prohance
Gadoterate - Dotarem
Linears a/w NSF
Gadodiamide - omniscan
Gadaversetamide - optimark
gadopentetate - magnevist
Die, adverse, petegram
the only O ones and Magnevist
epi IM and IV doses
IM 1:1000 0.3 ml (0.3mg)
IV 1:10,000 1 ml (0.1 mg)
during a code, IV epi 1:10,000 10 ml, 1 mg
Breast feeding and nuks
cessation
I 131
I 123 NaI
Gallium
breast feeding
pertechnetate
4 hours
breast feeding
thallium
96 hours
stable isotope of iodine?
I 127
administered activity
Thyroid uptake and scan
I 131
I 123
Pertech
I 131 10 MICRO
I 123 0.5 mCi
Pertech 2-10
PE, comptom Z and E
PE Z cubed / E cubed
Compton 1/E (but does depend on electron density)
Effective dose ballparks
PET
Cardiac CTA
chest CT
head CT
PET 10 + 15 mSv
Cardiac CTA 10 - 20 mSv
chest CT 5 - 7 mSv
head CT 1 - 2 mSv
? radiosensitivity
?marrow
breast
gonads
thyroid
skin
tube leakage should not exceed
1 mGy per hour at 1m from source
minimum aluminum requirement
2.5 mm
10 mGy in first trimester increased Ca risk
3.5 x
average US exposure background and medical
6 mSv
3mSv medical (mostly CT and nucs)
retardation
organogen
retardation 9-15
organs 2-8
BEIR VII risk of cancer mortality
5 % per Sv
power for a CXR
mammo
100 kW
mammo 3 kW
kub air kerma
3 mGy
kub entrance skin dose
PA chest
lateral L spine
5 mGy (50% more than entrance air kerma)
chest PA 0.2 mGy
lat L spine 15 mGy
good dose limiting strategy for
kids
fatties
kids = small focal spot
fatties = higher kVp
MTF describes
spatial resolution in the frequency domain
product of component MTF’s
Infection agent administered activities

Geiger is a
gas chamber
Well counter
na/I crystal with a PMT (small gamma camera)
Thyroid probe
small gamma camera, modified naI well counter (PMT and a crystal)
Geiger overwhelmed at
100 mR/h
Ion chamber
looks kinda like a Geiger, no dead time, up to 100 R/h
(most dose calibrators are ion chambers, gas)
lp’s/mm
screen mammo
digi mammo
digi rad
CT
MRI
screen mammo 15
digi mammo 7
digi rad 3
CT 0.7
MRI 0.3
entrance exposure rate for
Radiography
fluoro
Ir and cardiac cath
Radiography 3mGy/min
fluoro 30mGy/min
Ir and cardiac cath 300 mGy/min
File size
CXR
single CT image
CXR = 10 mb
CT image = 0.5 mb
AAST
Liver
grade I (tiny knick)
haematoma: subcapsular, <10% surface area
laceration: capsular tear, <1 cm parenchymal depth
grade II
subcapsular, 10-50% surface area laceration: capsular tear 1-3 cm parenchymal depth, <10 cm length
grade III
haematoma: subcapsular, >50% surface area of ruptured subcapsular or parenchymal haematoma
laceration: capsular tear >3 cm parenchymal depth
grade IV
laceration: parenchymal disruption involving 25-75% hepatic lobe or involves 1-3 Couinaud segments
Grade V = vascular hepatic avulsion
AAST
Kidney
grade I: contusion or non-enlarging subcapsular perirenal haematoma, and no laceration
grade II: superficial laceration <1 cm depth and does not involve the collecting system
grade III: laceration >1 cm without extension into the renal pelvis or collecting system (no evidence of urine extravasation)
grade IV
laceration extends to renal pelvis or urinary extravasation
vascular: injury to main renal artery or vein with contained haemorrhage
V = shattered, devascularized
AAST
spleen
grade I
subcapsular haematoma <10% of surface area
capsular laceration <1 cm depth
grade II
subcapsular haematoma 10-50% of surface area
intraparenchymal haematoma <5 cm in diameter
laceration 1-3 cm in depth not involving trabecular vessels
grade III
subcapsular haematoma >50% of surface area or expanding
intraparenchymal haematoma >5 cm or expanding
laceration >3 cm in depth or involving trabecular vessels
ruptured subcapsular or parenchymal haematoma
grade IV
laceration involving segmental or hilar vessels with major devascularisation (>25% of spleen)
grade V
shattered spleen
hilar vascular injury with splenic devascularisation