Cancer presentation by system and referral Flashcards

1
Q

What are some general red flags for cancer?

A

Weight loss
Loss of appetite
Night sweats
Fatigue

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2
Q

What are some paraneoplastic effects of cancer?

A

PUT AT THE END

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3
Q

When do you refer people for lung cancer?

A

Urgent appointment (<2wks) if:

  • CXR findings suggesting lung cancer
  • Aged >40yrs with unexplained haemoptysis
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4
Q

When do you offer an urgent CXR to assess for lung cancer?

A

Urgent = <2wks

People aged >40yrs if:

2+ of following unexplained symptoms or if they have ever smoked and have 1+ following unexplained symptoms

  • Cough
  • Fatigue
  • Shortness of breath
  • Chest pain
  • Weight loss
  • Appetite loss

Consider if:

  • Persistent/recurrent chest infections
  • Finger clubbing
  • Supraclavicular lymphadenoapathy or persistent cervical lymphadenopathy
  • Chest signs consistent with lung cancer
  • Thrombocytosis
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5
Q

When should you consider urgent CXR to check for mesothelioma?

A
Aged >40 if: 
2x following OR 1x following and have smoked OR 1x following and exposed to asbestos: 
- Cough 
- Fatigue 
- SOB
- Chest pain 
- Weight loss 
- Appetite loss 

Consider if:

  • Finger clubbing
  • Chest signs compatible with pleural disease

Urgent referral to suspected cancer pathway if CXR findings +ve

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6
Q

When should you refer someone using an urgent suspected cancer referral for colorectal cancer?

A

Age >40yrs with unexplained weight loss and abdo pain
OR
Aged >50yrs with unexplained rectal bleeding
OR
Aged >60yrs with iron deficiency anaemia OR change in bowel habit
OR
Tests show occult blood in faeces

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7
Q

What happens if you are suspicious of colorectal cancer but the person does not fulfil the urgent referral criteria?

A

If unexplained symptoms without rectal bleeding - test for occult blood in faeces:
- OC Sensor, HM‑JACKarc and FOB Gold quantitative faecal immunochemical tests

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8
Q

When should you refer someone using an urgent suspected cancer referral for breast cancer?

A

Aged >30 with an unexplained breast lump +/- pain OR
Aged >50 with any of the following symptoms in one nipple only:
- Discharge
- Retraction
- Other changes of concern

Consider urgent referral if:

  • Skin changes that suggest breast cancer
  • > 30yrs with unexplained lump in the axilla
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9
Q

When should you refer someone using an urgent suspected cancer referral for prostate cancer?

A

If their prostate feels malignant on digital rectal examination

If PSA levels are above the age specific reference range

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10
Q

When should you consider a PSA and DRE for prostate cancer?

A

Any LUTS e.g. nocturia, urinary frequency, hesitancy, retention
OR
Erectile dysfunction
OR visible haematuria

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11
Q

How should you manage a patient with suspected stomach cancer?

A

Consider urgent referral if:
- Upper GI mass consistent with stomach cancer

Offer urgent upper GI endoscopy if:

  • Dysphagia
  • > 55yrs with weight loss and ANY of: upper GI pain, reflux, dyspepsia
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12
Q

How do you manage a patient with suspected liver cancer?

A

Urgent USS liver in people with upper abdominal mass consistent with an enlarged liver

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13
Q

How should you manage a patient with suspected oesophageal cancer?

A

Urgent upper GI endoscopy if
- Dysphagia
OR
- Aged >55 wit ANY of the following: upper abdominal pain, reflux, dyspepsia

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14
Q

When should you refer someone using an urgent suspected cancer referral for cervical cancer?

A

If, on examination, the appearance of their cervix is consistent with cervical cancer

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15
Q

When should you refer someone using an urgent suspected cancer referral for thyroid cancer?

A

If patient has an unexplained thyroid lump

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16
Q

When should you refer someone using an urgent suspected cancer referral for bladder cancer?

A

Age >45 with
- Unexplained visible haematuria without UTI
OR
- Visible haematuria that persists after resolution of UTI
(these criteria are the same for renal cancer)

OR

Aged >60 with unexplained non-visible haematuria AND
Dysuria OR raised WCC

17
Q

When should you refer someone using an urgent suspected cancer referral for lymphoma?

A

Patients presenting with unexplained lymphadenopathy or splenomegaly

When referring, take into account associated symptoms especially fever, night sweats, shortness of breath, pruritis, weight loss

18
Q

When should you refer someone using an urgent suspected cancer referral for pancreatic cancer?

A

Aged >40 with jaundice

Consider urgent CT/USS if aged >40 with weight loss and ANY of the following:

  • Diarrhoea
  • Back pain
  • Abdominal pain
  • Nausea
  • Vomiting
  • Constipation
  • New onset diabetes
19
Q

How do you manage suspected leukaemia?

A

Very urgent (<48hrs) FBC to assess for leukaemia if any of the following:

  • Pallor
  • Persistent fatigue
  • Unexplained fever
  • Unexplained persistent or recurrent infection
  • Generalised lymhpadenopathy
  • Unexplained bruising
  • Unexplained bleeding
  • Unexplained petechiae
  • Hepatosplenomegaly
20
Q

When should you refer someone using an urgent suspected cancer referral for oral cancer?

A

unexplained ulceration in the oral cavity lasting for more than 3 weeks
OR
A persistent and unexplained lump in the neck

21
Q

When should you refer someone using an urgent suspected cancer referral for malignant melanoma of the skin?

A

If they have a score of 3 or more on the 7-point weighted checklist:

Major features: (2 points)

  • Change in size
  • irregualr shape
  • Irregular colour

Minor features: (1 point)

  • Largest diameter 7+mm
  • Inflammation
  • Oozing
  • Change in sensation
22
Q

How do you manage suspected myeloma?

A

Aged >60 with hypercalcaemia OR leukopenia
AND
A presentation consistent with possible myeloma:
- Very urgent (<48hrs) protein electrophoresis and a Bence-Joens protein urine test

Aged >60 with persistent bone pain (esp back pain) or unexplained fracture:

  • FBC
  • Calcium profile
  • Plasma viscosity/ESR