Cancer Oncogenes and tumour suppressor genes Flashcards

1
Q

Examples of oncogenes

A
EGFR, Her-2
SOS
ERK
Ras
c-Myc
cyclin D1
Raf
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2
Q

Examples of tumour suppressor genes

A
p53 (only one allele needs to be defective so shows oncogenic nature but is TSG as it inhbits proliferation)
APC
Fas receptor
PTEN
BRCA1
pRB
CIP/KIP family eg p27KIP1
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3
Q

Tumour suppressor gene definition

A

Genes involved in

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