Cancer Imaging Flashcards
PET-CT:
PET uses a non-specific radioactive tracer (FDG) which highlights areas of increased metabolism, cell proliferation, or hypoxia.
It therefore accumulates in cancer cells > non-cancer cells
PET-CT is a powerful combination of anatomical (CT) and functional (PET) information allowing diagnosis, increased accuracy of staging, and assessment of treatment response.
Monoclonal antibodies:
radio-labelled tumour antibodies specific to the tumour under investigation, eg prostate specific membrane antigen, somatostatin (neuroendocrine tumours), oestrogen receptor (breast).
They can offer better specificity than standard PET images
Bone scintigraphy (bone scan)
detects abnormal metabolic activity in bones