Cancer (general info)

Question 1

Aims of cancer

Answer 1

• Curative
• Prolong life
• Relief of palliative symptoms

Question 2

Neoadjuvant therapy

Answer 2

• Initial chemotherapy aimed at shrinking the primary tumour.
• Makes local therapy less destructive or more efffective.

Question 3

Adjuvant therapy

Answer 3

• Follows a definitive treatment of the primary disease where there is a high risk of sub-clinical metastatic disease

Question 4

Handling cytotoxic drugs

Answer 4

• Trained personnel
• Designated pharmacy area for reconstituting cytotoxic drugs.
• Protective clothing/cover eyes
• Pregnant staff should avoid exposure.
• Females of reproductive age should be informed of the risks.
• Local procedures for spillages and safe waste disposal.
• Monitor staff exposure

Question 5

Injectable cytotoxics

Answer 5

Should only be dispensed if they are prepared for administration

Question 6

Non-specialists

Answer 6

• Should have access to written protocols/treatment plan when prescribing or administering ongoing cytotoxic medicines
• Protocols include guidance on monitoring + treatment.

Question 7

Dispensing

Answer 7

• Confirm prescribed dose is appropriate
• Prescriptions must NOT be repeated unless specialist instructs
• Patient must have written information on their oral anti-cancer regimen which includes treatment plan and monitoring arrangements from original hospital protocol.
• Pharmacists must have access to this information and advice from experienced cancer pharmacist in initiating hospital