Cancer drugs Flashcards
1
Q
Induce free radical formation
A
Bleomycin
Dactinomycin
Doxo/daunorubicin
2
Q
Cross-link DNA
A
Busulfan
Cyclophosphamide, ifosfamide
Nitrosoureas
3
Q
Prevent mitotic spindle from breaking down
A
Taxols
4
Q
Prevent mitotic spindle formation
A
Vincristine
5
Q
Cross-links DNA
GU association
A
Cisplatin
Carboplatin
6
Q
Inhibit topoisomerase II
A
Etoposide
Teniposide
7
Q
Inhibit topoisomerase I
A
Irinotecan
Topotecan
8
Q
Inhibits ribonucleotide reductase
A
Hydroxyurea
9
Q
Monoclonal antibody against VEGF
A
Bevacizumab
10
Q
EGFR tyrosine kinase inhibitor
A
Erlotinib
11
Q
BCR-ABL tyrosine kinase inhibitor
A
Imatinib
12
Q
Monoclonal antibody against CD20
A
Rituximab
13
Q
Monoclonal antibody against HER-2 tyrosine kinase receptor
A
Trastuzumab
14
Q
BRAF inhibitor (for melanoma)
A
Vemurafenib
