CANCER DRUGS Flashcards
What drugs cause neuropathy?
taxanes, platinum (oxaliplatin), vinca alkaloids
What drugs cause cardiac toxicities?
anthracyclines (doxorubicin)
D around your heart
What causes hand-foot syndrome?
5FU/capecitabine (FUCK YOUR CAPACITY AND PUT YOUR HAND IN YOUR MOUTH)
What causes nephrotoxicity?
cisplatin (cisplat your kidneys dude)
What causes diarrhea?
5FU, irinotecan (FUCK YOUR DIARRHEA, IRINO U CAN DO IT)
Rituximab
Anti CD20 used in B cell lymphoma. (second line therapy in ITP and AIHA and TTP)
Traztuzumab
Breast cancer anti HER-2, cardiac toxicity
Bevacizumab
Anti VEGF-r, metastatic colon and non-small cell lung cancer, thrombosis, bleeding, TTP
Cetuximab
Anti EGFR metastatic colon and squamous head and neck, diarrhea/rash
Imantinib (Gleevec)
BCR-ABL TK (CML), C-Kit GIST
Edema, cramps, rash