Cáncer De Endometrio Flashcards

1
Q

Causa mas común ginecológica de malignidad

A

Cáncer de endometrio

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2
Q

Pico de incidencia para el CaEndometrio

A

60-70 años

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3
Q

Mortalidad anual del CaEndometrio

A

2%

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4
Q

Factores de riesgo para CaEndometrio

A
  • Tamoxifen
  • Síndrome de Lynch
  • DM
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5
Q

Etiología de síndrome de lynch

A

Mutacion en linea germinal de genes reparadores de DNA

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6
Q

Mutaciones comunes en síndrome de lynch

A

MLH1 y MSH2

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7
Q

Factores protectores para CaEndometrial

A
  • AOC

- Multiparidad

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8
Q

Presentación clínica de CaEndometrial

A
  • SUA 75-90%
  • > 55 años de edad
  • Descarga vaginal
  • Células glandulares atípicas en citología cervical
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9
Q

Prueba diagnóstica de CaEndometrial

A
  • Biopsia endometrial
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10
Q

Lesión precursora mas común de cancer endometrial

A

Hiperplasia endometrial

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11
Q

% de carcinoma endometrial de tipo 1

A

80%

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12
Q

¿Tumores tipo 1 en CaEnd son estrógeno inducidos?

A

Si

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13
Q

% de tumores tipo 2 en CaEnd

A

20%

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14
Q

Tratamiento de estadios tempranos de CaEnd

A
  • Histerectomía simple y SOP
  • Citología peritoneal
  • Evaluación de nódulos linfáticos regionales
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15
Q

Manejo medico de CaEnd

A
  • Terapia hormonal con progestinas
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