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Cancer care > Cancer care > Flashcards

Cancer care Flashcards

1
Q

What cancers are associated with tumour lysis syndrome

A

Lymphoma
Leukaemia

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2
Q

What is given to reduce the risk of tumour lysis syndrome

A

Allopurinol
Rasburicase

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3
Q

Electrolyte abnormalities in tumour lysis syndrome

A

High K+
High phosphate
Low Ca
High urate

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4
Q

Symptoms of tumour lysis syndrome

A

Nausea
Vomiting
Muscle pain
Dysuria
Oligouria
Weakness

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5
Q

Criteria for neutropenic sepsis

A

T >38.5 or 2 readings >38
Neutrophils <0.5

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6
Q

Risk factors for neutropenic sepsis

A

Sustained neutropenia >7days
Clinically unstable
High intensity chemotherapy
Significant co-morbidities

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7
Q

Management of neutropenic sepsis

A

IV piperacillin + tazocin
Fluoroquinolone prophylaxis

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8
Q

Cancers typically associated with SVCO

A

Non-small cell lung cancer
Small cell lung cancer
Lymphoma

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9
Q

Features of SVCO

A

Dyspnoea
Orthopnoea
Facial plethora
Dilated/engorged chest veins
+ve Pemberton’s test

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10
Q

Management of SVCO

A

PO dexamethasone
IVC stenting once stabilised

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11
Q

Cause of hypercalcaemia in malignancy

A

Tumour secretion of PTHrP
Increased osteoclast activity
Lymphoma cell production of calcitriol
Tumour production of PTH

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12
Q

Risk factors for hypercalcaemia of malignancy

A

Non-metastatic malignancy
Metastatic skeletal involvement
Lymphoma

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13
Q

Features of hypercalcaemia

A

Dry mucous membranes
Confusion
Fatigue
Constipation
Nausea
Loss of appetite
Polyuria
Bone pain

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14
Q

Management of hypercalaemia

A

Treat underlying malignancy
IV normal saline
IV bisphosphonate
Haloperidol

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15
Q

Antiemetic(s) of choice for chemical causes of nausea

A

Haloperidol (D2)
Metoclopramide (D2, 5HT3)

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16
Q

Antiemetic(s) of choice in gastric stasis

A

Metoclopramide (D2, 5HT3)
Domperidone (D2)

17
Q

Antiemetic(s) of choice in bowel obstruction

A

Cyclizine (H1, ACh)
Dexamethasone

18
Q

Antiemetic(s) of choice in raised ICP

A

Cyclizine (H1, ACh)
Dexamethasone

19
Q

Antiemetic of choice for psychological causes of nausea

A

Benzodiazepines

20
Q

Antiemetic of choice for post-op nausea

A

Ondansetron (5HT3)

21
Q

Stimulant laxatives

A

Senna
Bisacodyl

22
Q

Stool softener

23
Q

Osmotic lxatives

A

Lactulose
Movicol
Laxido

24
Q

When to use Tamoxifen for breast cancer

A

Oestrogen receptor +ve tumours
Premenopausal women

25
Q

When to use Letrozole/Anastrozole for breast cancer

A

Oestrogen receptor +ve tumours
Postmenopausal women

26
Q

When to use Herceptin for breast cancer

A

HER2 receptor +ve tumours

Cancer care (1 decks)

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