Cancer and Reproduction Flashcards
Dibromochloropropane (DBCP)
aka: Dow Birth Control Pill
nematocide in banana industry
decreased sperm count and motility
Which metal can affect the menstrual cycle
inorganic mercury
Known Teratogens (4)
DES
lead
antineoplstic meds
ionizing radiation
Normal sperm and ova count
15-200 million/ml & 1-2 million (will ovulate 400 in a lifetime
Reproductive Health Policy from 1991 Supreme Court Decision
Lead Battery Factory. pregnant/fertile employee gets to decide whether or not they want to continue working in a hazardous area after getting information on hazards/risks. Came from lead exposure (UAW v Johnson Controls)
Minamatta Disease
Pregnant women exposed to methylmercury. Placenta pulled it from mother’s blood stream and concentrated it in the fetus. Kids were diagnosed with CP, later realized looked just like the neurologic complications in other, nonpregnant, exposed adults
Carbon Disulfide effect on fertility
decrease sperm count and menstrual abnormalities
used in the rayon and rubber industry
Benzene effect on fertility
decrease sperm counts and menstrual abnormalities
Glycol ethers effect on fertility
general fertility issues
Ethylene dibromide effect on fertility
mutagenic and carcinogenic
Preconception Mutagenics
Organic solvents
Nickel
Arsenic
Occupation Causes of Lung Cancer
A^2BC^3RN
Asbestos Arsenic Bischlormethyl CCMD Chromium Coal Tar Pitch volatiles Radiation Nickel
OSHA and IARC Catgories
International Agency for Research on Cancer
1 - carcinogenic, sufficient evidence (121)
2A - probably carcinogenic, limited evidence (89)
2B - possibly carcinogenic, insufficient evidence (318)
3 - not classifiable as to its carcinogenicity (499)
4 - probably not carcinogenic (1)
Levels of prevention in the workplace (4)
- Engineering
- Work Practice Controls
- Administrative controls
- Personal Protective Equipment
Engineering controls
Tries to separate the person from the exposure
ex: guard rails, AC units near heat
Work practice controls
Elimination and Substitution
ex: using different metal for computer chip
Hexavalent chromium is associated with which cancer
Lung cancer
Benzene is associated with which cancers
leukemia (CML and A
absorbed through the lungs but NOT assoc with lung cancer
