Cancer and Gerontology Flashcards
What are the 3 main stages of cancer?
- Initiation
- Promotion
- Progression
What occurs in the Initiation stage of cancer?
cancer cells arise from normal cells, these cells develop mutations
What occurs in the promotion stage of cancer?
characterized by reversible proliferation of alt cells
What are some promoting factors in the promotion stage?
- dietary fat
- obesity
- cigarette smoking
- Ethol consumption
What is the key prevention in the 2nd stage?
activity of promoters are reversible
How is the 3rd stage of cancer characterized?
- increased growth rate of tumor
- invasiveness
- Metastasis
Where are the common locations cancer can metastasizes?
- brain and CSF
- lungs
- liver
- adrenals
- bone
What is cancer?
a group of > 200 diseases that are characterized by uncontrolled and unregulated growth of cells
List the 4 clinical staging classifications
Cancer in situ
SI: Tumor limited to tissue of origin; localized tumor growth
SII: Limited local spread
SIII: Extensive local and regional spread
SIV: Metastasis
Describe what is the TNM System
anatomic extent of disease is based on 3 parameters:
Tumor size and invasiveness
Spread to lymph nodes
Metastasis
At what and frequency should women get mammograms?
annually for women older than 40
At what age and frequency should adults screen for fecal occult blood?
annually for adults of all ages
At what age and frequency should men receive a digital rectal exam?
men older than 50 yrs
Who and at what age should they screen for colon cancer by getting a colonoscopy?
at age 50 and they q10yrs
At what age and freq should women receive a clinical breast exam?
annually for women older than 40 and q3yrs for women 20-39 yrs old