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med chem drugs > cancer > Flashcards

cancer Flashcards

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1
Q

mechlorethamine
melphalan
……

A

nitrogen mustards

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2
Q

cyclophosphamide

chlorambucil

A

phosphamide mustards?

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3
Q

carmustine
lomustine
streptozocin

A

nitrosoureas

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4
Q

cisplatin

carboplatin

A

platins

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5
Q

busulfan
thiotepa
procarbazine
dacarbazine

A

other alkylating agents

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6
Q

5 flourouracil

A

thymidylate synthase inhibitor

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7
Q

methotrexate

A

dihydrofolate reductase inhibitor

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8
Q

pemetrxed

A

TS and DHFR inhibitor

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9
Q

cytarabine
gemcitabine
methotrexate
5-FU

A

pyrimidine based antimetabolites

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10
Q

6-mercaptopurine
6-thioguanine
fludarabine
cladribine

A

purine antimetabolites

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11
Q

dexrazoxane

A

cardioprotective agent

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12
Q

doxorubicin

“rubicin”

A

anthracyclines

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13
Q

etoposide
amscrine
mitoxantrone

A

topoisomerase 2 inhibitors

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14
Q

camptothecins
topotecan
irinotecan

A

top 1 inhibitors

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15
Q

dactinomycin

A

actinomycins

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16
Q 
bleomycin
anthracycline
top 1 and 2 inhibitors 
actinomycins
mitomycins
A

antitumour antibodies

17
Q

Vinblastine

Vincristine

A

Vinca alkaloids

18
Q

Vinca alkaloids
Taxanes
Epithilones

A

Antimitotics

19
Q

Paclitaxel

Docetaxel

A

Taxane

20
Q

IXA

A

Epothilone

21
Q

Lapatinib

A

Small molecule tyrosine kinase inhibitor

22
Q

Traztuzumab

A

Monoclonal antibody

23
Q

Bortezomib

A

Proteasome inhibitor

24
Q

Carfilzomib

A

Tetrapeptide epoxyketone

Proteasome inhibitor?

med chem drugs (4 decks)

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