Cancer

Question 1

Radiosensitive testicular tumor

Answer 1

Seminoma

Question 2

Most common ovarian tumor type

Answer 2

Epithelial: malignant, older

Others:
Germ cell: benign, younger
Sex cord stromal: middle aged, hormone producing

Question 3

Schistosoma is associated with this cancer

Answer 3

Bladder squamous cell carcinoma

Question 4

Most common cervical cancer

Answer 4

Squamous Cell carcinoma

Question 5

Most common prostatic cancer

Answer 5

Adenocarcinoma

Question 6

Risk factors for Breast Cancer

Answer 6

Prolonged estrogen exposure

Diagnosis of DCIS, LCIS, intraductal papilloma

BRCA1/2 (also ovarian, prostate)

Question 7

Most common type of kidney tumor

Answer 7

Renal Cell (Clear Cell) carcinoma

Question 8

Tumor marker for ovarian cancer

Answer 8

CA-125

Question 9

Classic triad of kidney tumor symptoms/signs

Answer 9

Flank pain
Palpable mass
Hematuria

Usually INCIDENTAL CT finding

Question 10

Prostate cancer more common in

Answer 10

elderly
African Americans
high fat diet
Positive family hx (father, brother)

Question 11

Most common type of breast cancer

Answer 11

Invasive ductal carcinoma

Question 12

Estrogen dependent endometrial cancer

Answer 12

Endometrioid (better prognosis than atrophic type)

Question 13

Most common type of bladder cancer

Answer 13

Transitional cell/Urothelial carcinoma

Question 14

Tumor markers for breast cancer

Answer 14

ER, PR, HER2

Question 15

AFP tumor marker elevated would be suggestive of

Answer 15

Yolk sac or embryonal testicular tumor

Question 16

Associated with this renal cancer:

Von-Hippel-Lindau –>

Tuberous Sclerosis –>

Answer 16

VHL –> Clear cell carcinoma

TS –> Angiomyolipoma

Question 17

Bladder cancer is considered aggressive if it grows into this layer

Answer 17

Muscularis propria

Question 18

hCG tumor marker elevation would be suggestive of

Answer 18

Choriocarcinoma or Seminoma testicular cancer

Question 19

How do you stage esophageal cancer?

Answer 19

CT/PET for distant mets, EUS for local tumor invasion/lymph nodes

Question 20

What are symptoms of colorectal cancer?

Answer 20

Blood in stool, change in bowel pattern, abdominal pain

–> colonscopy with biopsy, CT, CEA, EUS or MRI

Question 21

CA 19-9 is a tumor marker for

Answer 21

Pancreatic cancer (primarily)
Colorectal cancer

Question 22

What are the unique screening recommendations for:

UC
PSC + UC
FAP
HNPCC

Answer 22

UC: 8 years p diagnosis
PSC+UC: when diagnosis made
FAP: start age 10
HNPCC: start age 20 or 10 years before relative dx (+ extracolonic screening)

Question 23

Head and neck cancers should be treated with

Answer 23

radiation, surgery

possibly PEG for nutritional support

Question 24

Who should be screened for colorectal caner if they have average risk?

Answer 24

50 yo with any screening modality

Question 25

Esophageal cancer will present with

Answer 25

progressive dysphagia, vomiting, fatigue, anemia, weight loss

Question 26

What colorectal screening methods can remove precancerous polyps?

Answer 26

Colonoscopy or flexible sigmoidoscopy

Question 27

How can you treat esophageal cancer?

Answer 27

Curative: endoscopic or surgery +/- chemo, radiation, NG tube for nutrition

Palliative: Esophageal stent, tumor debulking, PEG tube, chemo/radiation to prolong life

Question 28

If you have a first degree relative with CRC, when should you begin screening?

Answer 28

Age 40 or 10 years before their diagnosis age

Question 29

What are symptoms of pancreatic cancer?

Answer 29

jaundice, malabsorption, pruritis, abdominal pain

CT guided biopsy –> CT/EUS/CA19-9 to stage