Cancer

Question 1

Clinical fx of pineal gland mass

Answer 1

Parinaud syndrome (limited upward gaze, ptosis, upper eyelid retraction, pupillary abnormalities), obstructive hydrocephalus (papilledema, headache/vomiting, ataxia) and central precocious puberty.

Question 2

WAGR

Answer 2

Wilms tumor
Aniridia
Genitoruurinary anomalies
Mental Retardation (intellectual disability)

Question 3

DX of Wilm’s tumor

Answer 3

ABdominal ultrasound first. Followed by contrast CT of abdomen to evaluate nature and extent of the mass and of the chest to identify any pulm mets.