Cancer Flashcards

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1
Q

Cancer def

A
  • result of a mutation in genes that regulate mitosis
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2
Q

Benign

A
  • can grow large but at a very slow rate
  • non cancerous due to adhesion molecules
  • stick them together to a particular tissue
  • can be surrounded by a capsule so they can be easily removed via surgery without breaking off and spreading
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3
Q

Malignant tumours

A
  • can grow large
  • grow rapidly
    0 cancerous
  • can become unspecialised again
  • do not produce adhesive so metastasis occurs (breaking off and spreading)
  • can grow projections, forms secondary tumours
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4
Q

proto-oncogene

A

normal/unmutated genes that code for proteins and regulaate4 cell growth and differentiation

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5
Q

oncogne mutation

A
  • permanently activated
  • cells divide uncontrollably
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6
Q

Tumour suppressor gene

A
  • if mutated cell division could continue and mutated cells wouldn’t be identified and destroyed
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6
Q

Increased oestrogen

A
  • oestrogen produced in breast tissue after menopause
  • interferes with transcription of cell cycle genes
  • can lead to tumours
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