Cancer Flashcards

1
Q

Capacidad del sistema inmune de reconocer y eliminar celulas tumorales

A

Vigilancia inmunologica

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2
Q

Teoria que postula como las celulas neoplasicas burlan al SI

A

Teoria de la Inmunoedicion

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3
Q

Etapas de la teoria de la inmumoedicion

A

Eliminacion
Edicion (equilibrio)
Escape

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4
Q

Inmunovigilancia, SI reconoce y elimina celulas neoplasicas

A

Eliminacion

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5
Q

las celulas del cancer empiezan a mutar y seleccionan clonas que evaden la respuesta

A

Edición o equilibrio

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6
Q

Proliferacion de las celulas neoplasicas pq burlaron la respuesta inmune, manifestaciones clinicas

A

Escape

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7
Q

Ag prostatico sobreexpresado

A

APE

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8
Q

Oncofetal
Ca Colon / pancreas

A

ACE

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9
Q

Cancer Higado y celulas germinales

A

aFP (alfa proteina)

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10
Q

Cancer de ovario

A

Ca125

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11
Q

Normal en testiculo, pero en cancer de Melanoma

A

MAGE

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12
Q

Cancer Ductal mama

A

MUC-1

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13
Q

Mas usado en cancer de mama

A

HER2/NEU

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14
Q

Leucemias

A

CD10

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15
Q

Respuesta antitumoral del Th1

A

IFNy
activacion de M1
CTL

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16
Q

Respuesta antitumoral de NK

A

NKG2D > MICA/B

17
Q

Cual es la citocina q producen las celulas del cancer para evadir la respuesta?

A

TGF-B

18
Q

Ipilimumab a qn inhibe

A

Anti CTLA-4

19
Q

Rituximab inhibe a

A

Anti-CD20

20
Q

Transtuzumab inhibe a

A

Anti Her2/Neu

21
Q

Nivolumab

A

Anti PD-1