Cancer Flashcards
What Proteins Regulate the Cell?
Cyclins
What is the Importance of Cyclins?
They regulate the timing of the cell cycle
What is the Importance of Internal Regulators?
- Respond to events in the cell
- Allows cell cycle to proceed only if certain processes have happened
What is the Importance of External Regulators?
- Responds to events OUTSIDE of the cell
- Directs cells to speed up or slow down the cell cycle
- Stimulates growth and division of cells
What are Growth Factors?
One of the most important external regulators - Stimulates the growth and division of cells
What Causes Cancer?
Uncontrolled cell growth
What are the Masses Formed by Uncontrolled Cells Called?
Tumors
What do Tumors Do?
They lead to damage to the surrounding tissues.
What is Angiogenesis?
When tumors attract new blood vessel growth, shutting down blood flow to the cancerous cells.
- The cut of blood flow causes the cells to die
What are the 2 Types of Tumors?
Benign and Malignant
What is a Benign Tumor?
A tumor that remains at its original site.
- Can be removed surgically and/or killed by radiation
What is a Malignant Tumor?
A tumor where its cells break away and begin to spread, starting new tumors elsewhere
- Can be removed by chemotherapy, radiation and surgery
Are Cancer Cells Immortal or Non-Immortal?
Immortal
What Disease is Cancer?
Disease of Mitosis
- The regulating mitosis is ignored or overridden by the cancer cell
The Disease of Mitosis is Caused by Which Gene?
A defect in the P53 gene
