Cancer Flashcards
What are the risk factors for laryngeal cancer?
Tobacco, alcohol, poor nutrition, GERD/LPR, papilloma virus, weakened immune system
What is cancer?
Cancer is when a good cell goes bad. It occurs when there is damage to a cells’s suicide program, a cell does not receive or recognize suicide signals, defective genes for IDing DNA defects, or defective genes overriding the suicide.
What are the symptoms of alaryngeal cancer?
Persistent cough Persistent hoarseness Prolonged sore throat/ear pain Dysphagia Dyspnea/strider Unexplained weight loss Lump in the throat/neck
How is laryngeal cancer treated?
Radiation therapy, surgery, chemotherapy
How do cancer cells differ from normal cells?
Cancer cells function poorly or not at all and they reproduce too fast (rate of reproduction exceeds rate of death).
What are the stages based on and percentages of T stages
Location of the tumor, extent of the tumor, metastasis; Rate of node metastasis: T1: 1.9% T2: 16.7% T3: 25% T4: 65%
What are the effects of radiation on a laryngeal communication?
Xerostomia, dysphagia, decreased tissue compliance ( doesn’t vibrate very well), reduced loudness, decreased quality, decreased phonation time, slower speech rate, artificial larynx speech not necessarily effected, recovery in about 60 days.
What causes cancer?
Inheritance, a virus, chemicals, radiation.
Stage 0 (Carcinoma in Situ)
In stage 0, abnormal cells are found in the lining of the larynx. These abnormal cells may become cancer and spread into nearby normal tissue. Stage 0 is also called carcinoma in situ.
Stage I
In stage I, cancer has formed. Stage I laryngeal cancer depends on where cancer began in the larynx:
Supraglottis: Cancer is in one area of the supraglottis only and the vocal cords can move normally.
Glottis: Cancer is in one or both vocal cords and the vocal cords can move normally.
Subglottis: Cancer is in the subglottis only.
Stage 2
In stage II, cancer is in the larynx only. Stage II laryngeal cancer depends on where cancer began in the larynx:
Supraglottis: Cancer is in more than one area of the supraglottis or surrounding tissues.
Glottis: Cancer has spread to the supraglottis and/or the subglottis and/or the vocal cords cannot move normally.
Subglottis: Cancer has spread to one or both vocal cords, which may not move normally.
Stage 3
Stage III laryngeal cancer depends on whether cancer has spread from the supraglottis, glottis, or subglottis.
3 centimeters or smaller.
Stage 4
Spread to lymph node or outside of the neck.