Cancer Flashcards
Cancer has both a___as well as an environemental/behavioural component
genetic
Cancer is a ___disease that is the result of____. It is therefore more prevalent in older pop.
somatic
large number of mutations
The three main types of genetic mutations in cancer is associated with
oncogenes(growth)
tumour suppressor(stop)
DNA repair genes
The cell cycle consists of _____. There are checkpoints at —-
G1, S, G2 and M. Checkpoints at G1(start) and G2/M anaphase to metaphase transition
The cell cycle is regulated by ____and ___
cyclin-dependent kinase and ubiquities ligases
Benign
grow in a confined area
Malignant
capable of invading surrounding tissues as well as distal tissues by entering the blood stream
p53 is___.Rb is
p53 creats apoptosis which kills damaged DNA. Rb gives anitgrowth signals. Cancer cells loss both