Cancer Flashcards

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1
Q

Cancer has both a___as well as an environemental/behavioural component

A

genetic

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2
Q

Cancer is a ___disease that is the result of____. It is therefore more prevalent in older pop.

A

somatic
large number of mutations

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3
Q

The three main types of genetic mutations in cancer is associated with

A

oncogenes(growth)
tumour suppressor(stop)
DNA repair genes

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4
Q

The cell cycle consists of _____. There are checkpoints at —-

A

G1, S, G2 and M. Checkpoints at G1(start) and G2/M anaphase to metaphase transition

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5
Q

The cell cycle is regulated by ____and ___

A

cyclin-dependent kinase and ubiquities ligases

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6
Q

Benign

A

grow in a confined area

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7
Q

Malignant

A

capable of invading surrounding tissues as well as distal tissues by entering the blood stream

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8
Q

p53 is___.Rb is

A

p53 creats apoptosis which kills damaged DNA. Rb gives anitgrowth signals. Cancer cells loss both

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