Calculations

Question 1

Bioavailability

Answer 1

Question 2

Affinity

Answer 2

Question 3

Dissociation constant

Answer 3

Question 4

Vd

Answer 4

Question 5

time constant (tau)

Answer 5

Time constant

0.69

Question 6

t 1/2 (half life)

Answer 6

0.693 x tau
or
0.693 x (Vd/cl)

Question 7

Loading dose

Answer 7

Vd x Plasma conc.

Question 8

Maintenance dose

Answer 8

Plasma conc. x Cl

Question 9

Pressure

Answer 9

Pressure = force / area

Question 10

Poiseuille Equation

Answer 10

Question 11

Reynolds number

Answer 11

Reynolds number =
velocity x pressure x tube diameter / viscosity

Question 12

Boyle’s Law

Answer 12

PV = K

Question 13

Charle’s Law

Answer 13

V/T = K

Question 14

3rd Gass Law (guy-lussac)

Answer 14

P/T = K

Question 15

Combined gas law

Answer 15

PV / T = K
or
PV = nRT

Question 16

Power

Answer 16

Power (watts) = VI = I(squared) R

Question 17

Charge

Answer 17

Q= amperes x seconds
charge = Voltage x Capacitance

charge = coulombs
capacitance = farads

Question 18

Capacitance

Answer 18

Capacitance (C) = Q/V
Farads

Question 19

Defibrillator stored energy

Answer 19

stored energy = 1/2 x CV(squared)
or
1/2 QV

Question 20

Resistors

Question 21

Tension (tube)

Answer 21

P = T/r

Question 22

Tension (sphere)

Answer 22

P = 2T / r

Question 23

Work done

Answer 23

Work done = force x distance

Question 24

Humudity

Answer 24

Relative humidity = actual vapour pressure / saturated vapour pressure

Question 24

Total blood volume

Answer 24

Question 24

Starling Forces

Answer 24

Question 24

Stroke Volume

Answer 24

SV = EDV - ESV

Question 24

Plasma osmolality

Answer 24

Question 24

Nernst Equation

Answer 24

Question 25

Ejection fraction

Answer 25

SV / EDV

Question 26

Cardiac Output

Answer 26

CO = HR x SV

Question 27

Cardiac Index

Answer 27

CO/BSA (body surface area)

Question 28

Systemic Vascular Resistance

Answer 28

Question 29

Mean arterial blood pressure

Answer 29

MAP - CVP = CO x SVR

Question 30

Fick Method

Answer 30

Question 31

Ventilation

Answer 31

Question 32

Alveolar Gas Equation

Answer 32

Question 33

Bohr Equation

Answer 33

Question 34

Compliance

Question 35

Venous to arterial shunt

Answer 35

Question 36

Oxygen content

Answer 36

Question 37

pK

Answer 37

Question 38

Henderson-Hasselbach

Answer 38

Question 39

Cerebral perfusion pressure

Answer 39

CPP = MAP - (ICP+CVP)

Question 40

Clearance

Answer 40

clearance = Vd x K clearance = flow rate x extraction ratio

Question 41

Elimination

Answer 41

R elim = concentration x clearance R elim = Vd x K

Question 42

Bernoulli equation

Answer 42