Calcium/Phosphate Balance Flashcards

1
Q

Hypocalcemia S/S

A
  • “Bones, stones, groans, + moans”
  • Nerve/muscle excitability
  • Tetany (Trousaaeua + Chvostek sign)
  • Cardiac arrhythmia
  • Abdominal pain
  • Psych
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2
Q

Hypercalcemia S/S

A
  • DEC NM excitability

- Cardiac arrhythmia

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3
Q

Calcium distribution

A
  • 50% Free
  • 45% albumin-bound
  • 5% complexed w/ phosphate
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4
Q

Condition which cause Hypercalcemia

A
  • Hypervitaminosis D
  • Acidosis (Disrupts bound calcium -> INC Free)
  • Thiazide Diuretics (INC Reabsorption)
  • Hyperthyroidism
  • Malignancy (INC turnover)
  • Milk-Alkali syndrome
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5
Q

Conditions which causer Hypocalcemia

A
  • Alkalosis
  • Loop Diuretics
  • Hypoparathyroidism
  • Renal failure -> Hyperphospatemia
  • Pancreatitis (Saponification into necrotic fat)
  • Hypo/Hypermagnesemia
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6
Q

Hyperphosphatemia causes

A
  • Renal failure
  • Tumor lysis syndrome
  • Cell Lysis (Rhabdomyolysis)
  • Phosphate laxatives
  • Biphosponates/Acromegaly
  • Hypervitaminosis D
  • Hypoparathyroidism
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7
Q

Hypophosphatemia Causes

A
  • Hyperparathyroidism
  • Antacids
  • DKA
  • Refeeding syndrome (alcoholics)
  • Urinary wasting (fanconi)
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8
Q

Hypomagnesemia causes

A
  • Meds (Loop Diuretics, PPIs, some Abx, some chemotherepeutics)
  • Hypercalcemia
  • Alcoholism
  • Hyperthyroid, aldosterone, calemia
  • DM I + II
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