Calcium and phosphate metabolisms Flashcards
1
Q
Review the actions of PTH, vit D and FGF23 in maintaining plasma calcium and phosphate
A
recap prev notes
2
Q
Describe causes of hypercalcaemia and hypocalcaemia
A
- endocrine = hypogonadism, XS glucocorticoids, hyperparathyroidism, hyperthyroidism
- nutritional deficiency
- age
- malignancy
- renal disease
3
Q
Distinguish osteomalacia and osteoporosis
A
osteomalacia is loss of mineral conc in bone
osteoporosis is loss of bone mass (and thus mineral content too)
4
Q
Describe the diagnosis and treatment of osteoporosis
A
- measure bone density
score >= -2.5 = osteoporosis diagnosis
5
Q
Explain how disorders of calcium and phosphate metabolism in renal failure may impact bone health
A
renal failure = inappropriate phosphotase and vit.D metabolism
