Calcium Flashcards
how is calcium found in the body
diffusible
non- diffusible (bound to protein)
what 3 things maintain calcium homeostasis
parathyroid hormone
calcitonin
vitamin D
parathyroid hormone
secreted by parathyroid glands in response to low plasma [Ca]
acts to increase plasma [Ca] by..
increasing bone resorption
increasing Ca absorption in kidneys and intestines (helped by vit D inintestines)
calcitonin
secreted from thyroid glands
acts to decrease plasma calcium by ..
increasing bone formation
decreasing Ca resorption in the kidneys
hypocalcaemic tetany
decreased [Ca} leading to increased nerve excitability therefore muscle spasms / pins and needles
alkalosis
caused by hyperventilation (panic attack)
excessively alkaline condition of body that can cause low plasma [Ca]
remedy is to trap CO2 in lungs
hyperparathyroidism
over active parathyroid therefore excess bone resorption
hypoparathyroidism
under active parathyroids
can result in defective mineralisation of teeth
vitamin D deficiency
either dietary deficiency or failure of the body to synthesise
decreases Ca uptake in GIT therefore undermineralised bone that lacks rigidity
chidren - rickets
adults - osteomalacia