Calcitonin Flashcards
Calcitonin is produced by _____ cells of the thyroid gland in response to ________
Parafollicular (C-cells)
Hypercalcemia
2 main functions of calcitonin:
- decrease blood calcium
- Decrease bone loss and bone resorption
Calci-tone it down calcium
Increased calcium = ________ calcitonin release
Increased
Decreased calcium = _______ calcitonin release
Decreased
______ is a strong stimulator of calcitonin release
Gastrin
3 main things that control calcitonin secretion:
Calcium
Calcium sensing receptor
Gastric
Increased stimulation of calcium receptors = ______ release of calcitonin
Increased
Calcitonin decreases calcium in 2 main ways:
Decreasing osteoclast function (decreases bone resorption)
Increasing renal calcium elimination (decreasing renal calcium reabsorption)