CAI - Week 1 Flashcards
What are the 3 primary brain vesicles?
- Week 4
- Prosencephalon
- Mesencephalon
- Rhombencephalon
What are the 5 secondary brain vesicles
- Week 6
- Telencephalon
- Diencephalon
- Mesencephalon
- Metencephalon
- Myelencephalon
What secondary brain vesicles derive from Prosencephalon?
- Telencephalon
- Diencephalon
What secondary brain vesicle derives from Mesencephalon?
Mesencephalon
What secondary brain vesicles derive from Rhombencephalon?
- Metencephalon
- Myelencephalon
When do Cranial and Caudal Neuropores close during neural tube folding?
- Cranial - Day 25
- Caudal - Day 27
What happens if the cranial neuropore fails to close
- Anacephaly
- Fetal death in utero / neonate death
What occurs if there is failure of the caudal neuropore to fuse?
Spina bifida
What supplement prevents 70% of neural tube defects?
Folic acid
What the are the two divisions of the nervous system and what structures compose each?
- Central nervous system: Brain, Spinal cord, CN II
- Peripheral nervous system: Spinal nerves & Cranial nerves except CN II
What Cranial Nerve is part of the Central Nervous System?
CN II
Describe the two major cell types that compose the nervous system
- Neurons - Structural and functional units of nervous system, Carry afferent, efferent, and interneurons, rapid communication across synapses via NTs, composed of dendrites, soma, axons and axon terminals
- Neuroglia - Support, nourish, insulate the neurons. Non-neuronal, 5x more abundant
What neuroglia cells are found in the CNS
- oligodendrocytes
- astrocytes
- Microglia
- Ependymal cells
What neuroglial cells are found in the PNS
- Satellite cells
- Schwann cells
Describe the folding of the early embryological neural tube
During week 3 neural plate starts to thicken and elevate to become neural folds. Lift above and away from rest of ectoderm to approach at midline during folding. Fuses from cranial to caudal end to form neural tube. Cranial and caudal neuropores fuse together to close at day 25 and day 27 respective.