CAD & Thromboembolic Stroke: Part I Flashcards

1
Q

Nitrates: MOA

A
  • prodrug
  • Nitric Oxide (NO) stimulates conversion of GTP to cGMP
  • cGMP stimulates cGMP kinase
  • MAJOR effects: intracellular calcium decreases; MLC dephosphorylation
  • SMOOTH MUSCLE RELAXATION
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2
Q

Sildenafil (PDE-5 Inhibitor)

A

Viagra/Revatio

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3
Q

Tadalafil

A

Cialis/ Adcirca

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4
Q

Vardenafil

A

Levitra/Staxyn

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5
Q

Aggrenox

A

Aspirin/extended release Dipyridamole

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6
Q

Prasugrel

A

Effient

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7
Q

Clopidogrel

A

Plavix

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8
Q

Ticagrelor

A

Brilinta

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9
Q

Vorapaxar

A

Zontivity

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10
Q

Abciximab

A

Reopro

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11
Q

Eptifibatide

A

Integrilin

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12
Q

Tirofiban

A

Aggrastat

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13
Q

Alteplase

A

Activase

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14
Q

Reteplase

A

Retavase

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15
Q

Tenecteplase

A

TNKase

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16
Q

Ranolazine

A

Ranexa