CAD Flashcards
What is the main cause of CAD.
Atherosclerotic plaque
What is CAD.?
Impaired blood flow to the myocardium
Is CAD a normal part of aging?
Yes, it begins at 15
What is the final stage of the process of CAD?
The formation of atheromas, which are complex lesions if lipids, fibrous tissue, collagen, calcium, cellular debris, and capillaries.
What can happen to atheromas?
The calcified lesions can rupture or ulcer are and stimulate a thrombosis.
What are the modifiable risk factors for CAD?
Increased serum lipid levels HTN Cigarette smoking Obesity DM stress Physical activity
What are the unmodifiable risk factors for CAD?
Age
Gender
Ethnicity
Genetics
How can we decrease HTN?
Regular BP check ups (every 3 months) Adequate BP medications Decrease salt intake Stop smoking Control and reduce weight (regular exercise)
How can we decrease elevated serum lipid levels?
Check them every 90 days (start treatment when LDL is at 190)
Decrease total fat intake (decrease animal fat)
Maintain ideal body weight
Exercise programs
Increase complex carbs and veggies
What is the main way to reduce a stressful lifestyle?
REST AND SLEEP
How often a week should you exercise?
3-4 times a week?
What is stable angina?
Most common and predictable form of angina. Occurs with predictable amount of activity and is common manifestation if CAD.
What is prinzmetal angina?
Typical angina that occur unrelated to activity and often at night. It is caused by coronary artery spasm with or without an atherosclerotic lesion.
What is unstable angina?
Occurs with increasing frequency, severity, and duration. Pain in unpredictable and occurs with decreasing levels of activity or stress and may occur at rest.m
What is ACS?
Coronary blood flow is acutely reduced but not fully occluded.
What do most people with ACS have?
Stenosis of one or more coronary arteries.
What is the underlying cause of ACS?
Rupture or eroded plaque
What happens when the ACS plaque ruptures?
The exposed lipid core of the plaque stimulates platelet aggregation and the extrinsic clotting pathway. Thrombin is generated and fibrin is deposited, forming a clot that severely obstructs blood flow.m
What causes angina?
Lactic acid released from the ischemic cells stimulate he pain receptors.
How do stable lesions occlude?
They gradually occlude the vessel lumen
How do unstable lesions occlude?
Prone to rupture and thrombus formation
What do stable lesions cause?
Angina
What do unstable lesions cause?
ACS
When does an MI occur?
When blood flow to a portion of cardiac muscle is completely blocked. (Irreversible)
How long is the time frame for ischemia to get fixed before irreversible hypodermic damage occurs?
20 minutes
What does pain feel like with ACS?
Chest pain, usually subs thermal or epigastric. Radiates to the neck, left shoulder or arm. May occur at rest and normally lasts loner than 10-20 minutes
What are CM of ACS?
Dyspnea, diaphoresis, pallor, and cool clammy skin. Tachycardia and HTN.
How is an MI distinguished?
It’s duration and continuous nature.
What is the onset of pain with MI.?
Sudden and usually not associated with activity.