C251 Atrial Fibrillation Flashcards

1
Q

Most commom sustained arrythmia

A

Afib

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2
Q

Typical range of heartbeat in Afib

A

110-160 bpm

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3
Q

How many percent ng cardiac surgery post op patients ang nag AF

A

30%

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4
Q

Kelan magiging paroxysmal vs persistent vs longstanding persistent AF

A
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5
Q

Heart thrombus occurs primarily in

A

Left atrial appendage

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6
Q

Is tachycardia-induced cardiomyopathy reversible

A

Yes

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7
Q

Which chamber of the heart is most dilated in AF

A

left atrium

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8
Q

Drug used for Pharmacologic cardioversion of AF

A

ibutilide (class 3 antiarrhythmic)

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9
Q

Ibutilide should be avoided in patients with _________or _____________, given the risk of torsades des pointes.

A

Ibutilide should be avoided in patients with baseline prolonged QT interval or Severe left ventricular dysfunction, given the risk of torsades des pointes.

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10
Q

It is presumed that if the presenting episode of AF is >48 h or if the episode duration is unknown, there is risk for precipitating a thromboembolic complication through cardioversion, whether electrical or pharmacologically achieved.
Therefore, in this circumstance, the patient should be either
(1) _____ or
(2) _________

A

It is presumed that if the presenting episode of AF is >48 h or if the episode duration is unknown, there is risk for precipitating a thromboembolic complication through cardioversion, whether electrical or pharmacologically achieved.
Therefore, in this circumstance, the patient should be either
(1) initiated on anticoagulation, with cardioversion deferred for at least 4 weeks after uninterrupted anticoagulation, or (2) evaluated to exclude the presence of left atrial appendage thrombus.

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11
Q

f the duration of AF exceeds 48 h or is unknown, there is greater concern for thromboembolism after cardioversion, even in patients considered low risk

There are 2 approaches to mitigate the risk r/t cardioversjon. What…

A

f the duration of AF exceeds 48 h or is unknown, there is greater concern for thromboembolism after cardioversion, even in patients considered low risk

There are 2 approaches to mitigate the risk r/t cardioversjon.

(1) One option is to anticoagulate continuously for
eeks before and a minimum of 4 weeks after cardioversion.

(2) second approach is to start anticoagulation and perform a TEE or high-resolution cardiac CT scan to detect the presence of thrombus in the left atrial appendage. If thrombus is absent, cardioversion can be performed and anticoagulation continued for a minimum of 4 weeks to allow time for recovery of atrial mechanical function.

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12
Q

Adequate rate control in AF is defined as ______

A

Adequate rate control in AF is defined as a resting heart rate of <80 beats/min that increases to <100 beats/min with light exer-tion, such as walking.

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13
Q

In CHADSVAC, Anticoagulation is currently recommended for patients with a score of at least 1, unless the lone risk factor is female gender

A

In CHADSVASC, Anticoagulation is currently recommended for patients with a score of at least 1, unless the lone risk factor is _________

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14
Q

Components of CHADSVASC and HASBLED

A
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15
Q

Examples of oral factor Xa inhibitor

A

Apixaban
Edoxaban
Rivaroxaban

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16
Q

Example of antithrombin inhibitor

A

Dabigatran

17
Q

Example of vitamin K antagonist

A

Warfarin

18
Q

Warfarin is warranted for anticoagulation in these 2 conditions

A

Rheumatic mitral stenosis

Mechanical heart valves

19
Q

Required PT/INR ratio for warfarin to achieve therapeutic effect

A

> 2

20
Q

Direct acting anticoagulants cannot be used if with crea clearance of ____

A

<15

21
Q

This anticoagulant has safety and efficacy in px undergoing HD for ESRD

A

Apixaban

22
Q

How to reverse:
Warfarin
Dabigatran
Xa inhibitors

A

WARFARIN: vitamin K, FFP, Prothrombin complex concentrate

Dabigatran: idarucizumab

Xa inhibitors: Andexanet alfa

23
Q

Standard vs reduced dose of
Dabigatran, Rivaroxaban, Apixaban, Edoxaban

A
24
Q

Dose reduction criteria for dabigatran vs rivaroxaban va apixaban vs edoxaban

A
25
Q

Which can be used for px with structural heart disease… class I or class III antiarrhythmicsc

A

Class III: sotalol and dofetilide

26
Q

Catheter ablation has a _____% risk of major procedure-related complications

A

Catheter ablation has a 2-7% risk of major procedure-related complications,

27
Q

Percent risk of stroke vs cardiac tamponade in catheter ablatiom

A

Stroke: 0.5-1%

Cardiac tamponade: 1%

28
Q

This complication of catheter ablatiom presents with dyspnea or hemoptysis occuring usually after weeks to months from the procedure

A

PV stenosis

29
Q

Catheter ablation has the ff class recommendation….
1. Paroxysmal
2. Persistent AF without major risks for recurrence
3. HFREF

A
  1. Paroxysmal - Class IIa
  2. Persistent AF without major risks for recurrence - Class IIb
  3. HFREF - Class I