C-Section and PROM Flashcards

1
Q

Classification of C-Sections?

A
  • C-section is the delivery of a baby through a surgical incision in the abdomen and uterus.
  • They are either elective or emergency.
  • Emergency C-sections can then be sub-classified into 3 categories depending on their urgency.
  • Emergency C-sections most commonly for failure to progress into labour or suspected/confirmed foetal compromise.
  • Class 1 - Immediate threat to life of mother or foetus. (Should be born within 30 minutes)
  • Class 2 - Maternal or foetal compromise that is not immediately life threatening. (Should be born within 60-75 minutes)
  • Class 3 - No maternal or foetal compromise but needs early delivery.
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2
Q

Indications for elective C-Sections?

A
  • Breech presentation
  • Other malpresentations - transverse/oblique lie
  • Twin pregnancies - first twin not cephalic
  • Foetal compromise - early growth restriction/abnormal doppler
  • Transmissible disease - poorly controlled HIV
  • Maternal request
  • Maternal diabetes - with baby >4.5kg EFW
  • Maternal medical conditions - e.g. cardiomyopathy
  • Placenta praevia - low lying placenta
  • Primary genital herpes - HSV in 3rd trimester
  • Previous 3rd/4th tear
  • Previous major shoulder dystocia

Usually planned after 39 weeks to reduce respiratory distress in neonate (TTON), administration of corticosteroids to mother if delivery induced <39 weeks to stimulate surfactant development in foetal lungs.

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3
Q

Pre-op theatre procedure of C-sections brief:

A
  • FBC and Group + Save should be taken (blood loss in C-sections can be excessive)
  • H2 antagonists prescribed (Ranitidine +/- Metoclopromide) - pregnant women lying flat for C-section at risk of Mendelson’s syndrome (aspiration of gastric contents into lung causing chemical pneumonitis)
  • Risk score for VTE - compression stockings and LMWH prescribed as appropriate.
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4
Q

Anaesthesia in C-sections?

A
  • Usually performed under regional analgesia - ‘topped-up’ epidural or spinal anaesthetic
  • Some times General is required - due to maternal CI to regional, failure of regional to achieve required block, or most commonly concerns about foetal wellbeing and the need to expedite delivery ASAP (often case for Cat 1 C-sections).
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5
Q

Operative procedure:

A
  • Left lateral tilt of 15 degrees- reduce risk of supine hypotension due to aortacaval compression.
  • Indwelling Foley’s catheter inserted when anaesthetic is ready - drain bladder and reduce risk of bladder injury during procedure.
  • Skin prepared with antiseptic and antibiotics administered prior to incision.
  • Traverse lower abdominal skin incision (Pfannelstiel/Joel-Cohen) > sharp/blunt dissection through several layers: skin, Camper’s + Scarpa’s fascias, rectus sheath + muscle, parietal peritoneum, revealing gravid uterus.
  • Visceral peritoneum covering lower segment incised > pushed down and bladder retraced by Doyen retractor.
  • Uterine incision made on lower uterine segment - baby delivered in cephalic/breech presentation with fundal pressure.
  • Oxytocin 5iu given IV by anaesthetist to aid delivery of the placenta by controlled cord traction by surgeon.
  • Uterine cavity ensured empty - closed with 2 layers, rectus sheath closed and then skin (with sutures/staples).
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6
Q

Post-OP:

A
  • Observations recorded on early warning score chart, and loch (PV blood loss post delivery) monitored.
  • Early mobilisation, earring and drinking, removal of catheter encouraged to enhance recovery.
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7
Q

Reduced risks of C-Section?

A
  • Reduced risk: perineal trauma, pain, neonatal infection, incontinence, prolapse, late stillbirth.
  • Has immediate, intermediate and late complications.
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8
Q

Immediate complications of C-section?

A

1) PPH
2) Wound haematoma (large BMI/diabetes/immunosuppressed)
3) Intra-abdominal haemorrhage
4) Bladder/bowel trauma (previous abdominal surgery)
5) Neonatal: TTON, foetal lacerations

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9
Q

Intermediate complications of C-Section?

A

1) Infection - UTI, respiratory, endometritis

2) VTE

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10
Q

Late complications of C-Section?

A

1) Fistulae (UT trauma)
2) Psychological
3) Subfertility
4) Rupture of scar at next labour
5) Placenta praviae/accrete
6) Caesarian scar ectopic pregnancy

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11
Q

What is PROM and P-PROM?

A

Two main classifications of premature membrane rupture:

1) PROM - Rupture of foetal membranes at least 1 hour prior to onset of labour at >37 weeks gestation - minimal risk (as advanced gestation).
2) P-PROM - Rupture of membranes occurring at <37weeks gestation - higher rates of maternal and foetal complications. (associated with 40% of pre-term deliveries.

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12
Q

Ax and PPx of PROM (+ P-PROM)?

A
  • Foetal membranes consist of the chorion and amnion - strengthened by colleges and under normal circumstances they become weaker at term in preparation of labour.
  • Weakening occurs due to apoptosis and collagen breakdown by enzymes.
  • In PROM- and P-PROM, weakening and rupture occurs early: early activation of normal physiological process (higher levels of apoptotic markers and MMPs in amniotic fluid) and infection - inflammatory markers/cytokines contribute to weakening of membranes.
  • 3 factors can lead to early weakening - early activation of normal physiology, infection, genetic predisposition.
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13
Q

Risk factors of PROM and P-PROM?

A

1) Smoking
2) Previous PROM/pre-term delivery
3) Vaginal bleeding during pregnancy
4) Lower genital tract infection
5) Polyhydramnios
6) Multiple pregnancies
7) Amniocentesis
8) Cervical insufficiency

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14
Q

Clinical features of PROM/P-PROM?

A

1) Hx of BROKEN WATERS - painless popping and gush of watery fluid leak from vagina.
2) Can be non-specific - gradual leakage of fluid from vagina/damp underwear pad/change in discharge consistency
3) Speculum exam - fluid drainage from cervix, pooling in posterior vaginal fornix
4) Lack of normal vaginal discharge ‘washed clean’ - suggestive of rupture of membranes

Tests: Ask woman to cough during examination- can cause dispelling of amniotic fluid.
AVOID performing digital vaginal examination until active labour in women with suspected PROM/P-PROM.

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15
Q

Ddx of PROM/P-PROM?

A

1) Urinary incontinence
2) Normal vaginal discharge during pregnancy
3) Increased sweat/moisture
4) Increased cervical discharge (infection)
5) Vesicovaginal discharge
6) Loss of mucus plug

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16
Q

Investigations of PROM/P-PROM?

A

Made by 1) History and 2) positive examination findings, ultrasound not routinely used by may facilitate diagnosis if unclear - will show reduced levels of amniotic fluid within uterus.
1) HIGH VAGINAL SWAB - GBS would indicate antibiotics in labour, bacterial vaginosis implicated commonly as a cause for PPROM.
Other tests:
2) Ferning test - cervical secretion onto glass side allowing it to dry - fern-patterned crystals indicate positive
3) Actim-prom/medix biochemical - swab test for IGFBP1
4) Amnisure/QiaGen - PAMG-1
5) Nitrazine test - Measures pH of vagina - high risk of false positives due to contamination by urine/blood/semen no longer used.

17
Q

Management of PROM/P-PROM?

A

Rupture of foetal membranes release amniotic fluid which acts to stimulate uterus - majority will fall into labour within 24-48 hours - difficult to halt this. If labour does not start weight up watchful waiting vs IOL - when formulating appropriate management for PROM women.

1) <34 weeks - aim to increase gestation - monitor signs of clinical chorioamnionitis - avoid sex (risk of infection) - prophylactic erythromycin 250mg QDS for 10 days, corticosteroids, aim to wait until 34 weeks.
2) 34-36 weeks - monitor chorioamnionitis signs, avoid sex - prophylactic erythromycin 250mg QDS 10 days, corticosteroids - IOL AND DELIVERY RECOMMENDED.
3) >36 weeks - Monitor signs of clinical chorioamnionitis, clindamycin/penicillin if GBS isolated, watch and wait for 24hrs as most go into labour naturally, or consider IOL - IOL and delivery recommended after 24 hours - women can wait up to 96hrs - their choice after counselling.

18
Q

Complications of PROM?

A
  • Correlates with gestational age of foetus, majority of women at term will spontaneously labour at 24 hours after rupture - greater latency younger the gestational age - predisposed risk of maternal/foetal complications:

1) CHORIOAMNIONITIS - inflammation of membranes due to infection - risk increases longer the membranes remain ruptured without delivery.
2) OLIGOHYDRAMNIOS - if gestational age less than 24 wks this significant as increases risk of lung hypoplasia.
3) NEONATAL DEATH - complications with prematurity, sepsis and pulmonary hypoplasia
4) Placental abruption
5) Cord Prolaspse