C/O 2021 Buckets Flashcards
Treatment of MSSA
- Methicillin
- Oxacillin
- Dicloxacillin - DOC
- Cloxacillin
- Anything that covers MRSA
Treatment of community acquired MRSA
- Bactrim DS (PO) - DOC
- Clindamycin (PO) if Bactrim not an option
- Doxycycline (PO)
- Mupirocin (colonization) (topical)
Treatment of hospital acquired MRSA
- Vancomycin (IV)
- Linezolid (PO)
- Daptomycin (IV)
Treatment of VRE
- Linezolid (PO)
2. Daptomycin (IV)
Treatment of VRSA
- Daptomycin (IV)
Treatment of C. Diff
- Vancomycin (PO)
Treatment of community acquired pneumonia
- Doxycycline - DOC
- Amoxicillin
- Augmentin
- 2nd/3rd Gen Cephalosporins
- Macrolide
- Levofloxacin
Treatment of pseudomonas (worst gram negative)
- Extended-spectrum PCNs (IV)
- Ceftazidime (IV)
- Ciprofloxacin (PO)
- Imipenem (IV)
- Aminoglycoside (IV) use as adjunct
Treatment of enterococcus (worst gram positive)
- Ampicillin (PO/IV)
- Daptomycin (IV)
- Aminoglycosides (IV)
- Vancomycin (IV)
Treatment of UTIs
- Bactrim SS (PO) non-pregnant women DOC
- Nitrofurantoin (PO) pregnant & chronic UTIs DOC
- Amoxicillin (PO)
Treatment of STIs
- Syphilis – Pen G Benzathine LA (IM)
- Neurosyphilis – Pen G (IV)
- Chlamydia – Ceftriaxone (IM) & Azithromycin (PO)
- Gonorrhea – Ceftriaxone (IM) & Azithromycin (PO)
- Trichomoniasis – Metronidazole
Treatment of atypical bacteria (Legionella, Mycobacterium, Chlamydia)
- Macrolides (PO)
Treatment of anaerobes
- Clindamycin (PO)
2. Metronidazole (PO)
Abx that are gram positive only
- Penicillin (PO, IV)
- Antistaphylococcal PCNs (PO, IV)
- 1st Gen. Cephalosporins (PO)
- Vancomycin (PO, IV)
- Levofloxacin, Ofloxacin (fluoroquinolones)
- Clindamycin (PO)
- Mupirocin (topical)
Abx that are gram negative only
- Extended Spectrum PCNs (IV)
- Third Gen. Cephalosporins (PO)
- Ciprofloxacin (Fluoroquinolone)
- Metronidazole
- Aminoglycosides
Abx that cover both gram positive and negative
- Aminopenicillins (PO)
- 2nd Gen. Cephalosporins (PO)
- Carbapenems
- Macrolides (PO, IV)
- Tetracyclines (PO, IV)
- Bactrim (trimethoprim/sulfamethoxazole)
Treatment of tick-borne (Lyme) diseases
- Tetracyclines (PO) - Doxycycline DOC
2. Amoxicillin if pregnant
Treatment of hepatic encephalopathy.
- Neomycin (PO)
2. Rifaximin (PO)
Treatment of protozoa (Giardia)
- Metronidazole
2. Nitazoxanide
Contraindicated in pregnancy
- Fluoroquinolones
- Tetracyclines
- Bactrim
- NSAIDs (especially with Misoprostol)
- Azoles
- Warfarin (Heparin is a better option)
- Diabetes Oral Agents (switch to Insulin)
- ACEi/ARBs
- Misoprostol
- Ipecac (relatively contraindicated)
- Live vaccines
- Benzimidazoles
- Ivermectin
- Praziquantel
Contraindicated in children
- Fluoroquinolones (<16/18 y/o)
- Tetracyclines (children <8 y/o)
- Aspirin (<16 y/o) (can lead to Reye’s Syndrome)
- Baloxavir (<12 y/o)
- Ipecac (<6 mos)
Chelating agents
- Fluoroquinolones
- Tetracyclines
- Baloxavir
- Levothyroxine
- Sucralfate
- Antacids
Treatment of HSV-1, HSV-2, & Varicella Zoster
- Acyclovir
- Valacyclovir
- Penciclovir
- Famciclovir
Treatment of CMV
- Ganciclovir
- Valganciclovir
- Foscarnet
- Cidofovir
Treatment of patent ductus arteriosus
- Indomethacin (IV)
2. Ibuprofen Lysine (IV)
Drugs that decrease seizure threshold
- Meperidine
- Tramadol
- Theophylline
- Carbapenems
- TCAs
- Flumazenil
- Bupropion
- Haloperidol
Drugs that are renally eliminated
- PCNs
- Opioids
- Fluoroquinolones
- Aminopenicillans
- Digoxin
- H2RAs
- ULTs (Allopurinol, Febuxostat, Lesinurad, Probenecid, Pegloticase)
- Pravastatin
- Fibrates
- Ethambutol
Drugs that are hepatically eliminated
- Macrolides
- Tetracyclines
- -Azoles (except fluconazole, IV Vori)
- PPIs
- Statins (except pravastatin)
- Benzodiazepines
Drugs that are nephrotoxic
- Vancomycin
- Macrolides
- NSAIDS (Sulindac is the least)
- Cyclodextrin (IV Vori)
- Ampho B
- Imipenem (w Cilastatin to help)
- Outdated Tetracyclines
- Aminoglycosides
- Foscarnet
- Cidofovir
- Renin Inhibitors
- Entresto (Sacubitril & Valsartan)
Drugs that are hepatotoxic
- APAP
- -azoles (not IV Vori)
- Allylamines
- Isoniazid
Sulfa drugs or drugs with a sulfa-moiety
- Darunavir
- Acetazolamide (CA-inhibit)
- HCTZ
- Furosemide
- Sulfonylureas
- Celecoxib
- Bactrim
Treatment of thyroid storm
- Propranolol
- Dexamethasone (high dose)
- PTU if pregnant
Treatment of DKA
- Insulin ggt in NS
2. Phosphate and potassium replacement
Treatment of myxedema coma
- T3 - IV
HIV drugs that also cover Hep B
- Lamivudine
- Emtricitabine
- Tenofovir
Drugs that are highly plasma protein bound
- Warfarin
- Sulfonylureas (Glipizide, Glymperide, Glyburide)
- Aspirin/NSAIDs
- Bactrim
Drugs that require acid for better absorption
- Itraconazole
- Digoxin
- Atazanavir
- Iron
Drugs that cause QT prolongation
- Methadone
- Fluconazole (all -azoles except Isavuconazole, which will shorten QT)
- Cisapride
- ALL antipsychotics
Immunizations that are live
- MMR
- Zoster (Zostavax)
- Varicella (Varivax)
- Typhoid, oral
- Polio, oral
- Flumist, intranasal
- Rotavirus
Anticholinergic medications
- Atropine
- Dicyclomine (GI specific)
- TCAs (Imipramine, Nortriptyline, Amitriptyline)
Medications that require monitoring of TSH
- Amiodarone
2. Lithium
Medications with off-label indication for insomnia
- Diphenhydramine (Benadryl)
- TCAs (Amitriptyline, Nortriptyline)
- Trazodone
- Mirtazapine (Remeron)
- Quetiapine (Seroquel)
- BDZs - Temazepam (Restoril)
- Melatonin (jet-lag)
Treatment of enuresis (bed wetting)
- TCA - Amitriptyline, Nortriptyline
- Duloxetine (Cymbalta)
- Atomoxetine (Strattera)