C-en-es Flashcards

1
Q

Hemangioblastoma at Cerebellum

Associated with renal cell carcinoma

A

Von hippel Lindau

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2
Q

Paraneoplastic syndromes in CNS

A

Lambert Eaton myasthenic syndrome - associated with lung cancer (small cell)

> voltage gated ca+ ch
ca+ , presynaptic

Myasthenia graves - thymomas

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3
Q

Gliomas

A

Astrocytomas
Oligodendrocytes
Ependymoma

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4
Q

Neuronaltumors

A

Gangliomas

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5
Q

Poorly differentiated cns tumors

A

Medulloblastoma

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6
Q

CNS astrocytoma
Hair like structure in microscope
Relatively benign behavior
WHO CLASS 1

A

Pilocytic astrocytoma

Pediatric age group
“Pilo - hair like structure “

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7
Q

Astrocytoma

Mc location : cerebral hemispheres

Relatively malignant behavior

A

Infiltrating astrocytoma

  1. Diffuse (2/4)
  2. Anaplastic (3/4) greater nuclear polymorphism
  3. Glioblastoma(4/4)-mc primary brain tumor in adult

Frontal -weakness of legs
Pariatal - language

Radiotherapy & resec

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8
Q

Similar to a aplastic but with NECROSIS AND VASCULAR/ENDOTHELIAL CELL PROLIFERATION
“Butterfly lesion” in the brain
“Pseudo-palisading”

A

GLIOBLASTOMA MULTIFORME
WHO (4/4)

Most aggressive

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9
Q

Structure that connects the 2 cerebral hemispheres

A

Corpus callousum

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10
Q

Fried egg appearance
Mc location : cerebral hemispheres - WHITE MATTER
PP : sheath of irregular cells with spherical nuclei surrounded by clear halo

A

Oligodendroglioma

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11
Q

Mc CNS neoplasm associated with AIDS ,transplant,
EBV,marker = CD20
most common : DIFFUSE B CELL LYMPHOMA

A

Primary CNS lymphoma

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12
Q

Fever,rash, cervical and axillary LN Enlargement,hepato and splenomegaly
Heterophil (+)
Sore throat
Kissing disease

A

Infectious mononucleosis

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13
Q
Benign tumors of adult 
Attached to dura,meningothelial cells
Rf = prior radiotherapy 
Associated with NEUROFIBROMATosIS 2 
Psammoma bodies 
Atypical and anaplastic - most aggressive
A

MENINGIOMA

Mc site : parasagittal aspect ,dura over lateral con exits,sella Turkic a,f. Magnum,sphenoid wing

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14
Q

Foster Kennedy syndrome

A

Meningioma at olfactory groove

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15
Q

3 tumors with PSAMMOMA BODIES

A

Ovarian cyst-adenocarcinoma
Papillary thyroid cancer
Meningioma

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16
Q

Dural tail sign

A

Meningioma radiologic findings

17
Q
Ash leaf spots 
Shagreen patch 
Heart rehabdomyosarc
Lung hamartoma
Epilepsy 
Angiomyolipoma
Facial angiofibroma
A

TUBEROUS SCLEROSIS

18
Q

NEUROFIBROMATosIS 1 :

NEUROFIBROMATosIS 2

A
  1. NEUROFIBROMA - peripheral nerve & optic nerve
    > linchpin nodules
    > cafe au lait
  2. Bilateral acoustic neuroma
    Multiple meningioma
    SC EPENDYMoma