C. elegans Flashcards
1
Q
unc-6
A
gene
2
Q
Unc
A
Phenotype
3
Q
UNC-6
A
Protein
4
Q
Why study worms? 10
A
Simple, but complex
Phylogenetically close to humans as any other invertebrate
Nonparasitic
Rapid generation time
Transparent
Stereotyped embryogenesis
Cheap
Genetics
Sequenced genome
RNAi/CRISPR
5
Q
What was the proof of concept for the human genome project?
A
The first sequenced metazoan genome in 1998
6
Q
What is the most numerous animal on earth?
A
Nematode
7
Q
What is RNi?
A
RNA interference, take any gene and make a dbRNA and introduce it into cell, the cell thinks that it is a virus or a transposable element, chops it up and uses the pieces as guides to find more RNA
8
Q
Hermaphrodite
A
self-fertile
9
Q
How can you tell the males and hermaphrodites apart?
A
Tails
Male - blunt end
Hermaphrodite - tapered end
