C. 2nd Line of Defense of Innate Localized Acute Inflammation

Question 1

four signs of acute inlfammation

Answer 1

redness, heat, edema (swelling) and pain

Question 2

in the innate immune system inflammation includes

Answer 2

complement and phagocytes

Question 3

signaling by various inflammatory mediators cause

Answer 3

the endothelial cells to express selectin and CXCL8 which enables tight binding by neutrophils

Question 4

fn of capillary dilation and leakiness

Answer 4

facilitates neutrophil tight binding and extravastion

Question 5

fn of chemoattractants like CXCL8 and C3a and C5a

Answer 5

attract neutrophils to infected area

Question 6

fn of toll-like receptors and C3bR of neutrophil

Answer 6

enhance attachment to the bacteria

Question 7

capillary leakiness causes complement proteins to

Answer 7

enter the tisses. bacteria in tissues will activate the alternate and or lectin complement pathways

Question 8

MAC affects which gram bacteria

Answer 8

negative

Question 9

C3a and C5a fn

Answer 9

bind to receptors on mast cell causing histamine release. histamine contributes to vasodilation and capillary leakiness