Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

M2M > By the numbers > Flashcards

By the numbers Flashcards

1
Q

Imprinted genes in the human genome (percentage)

A

10%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

How large is the haploid human genome sequence?

A

3x10^9 base pairs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

How many mutations occur in each individual?

A

approximately 30

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

How many SNPs are there between any two individuals?

A

1 in every 1000 bp = 3,000,000 but we are 99.9% identical

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What percentage of the genome is GC rich vs AT rich

A

38% GC, 54% AT. This is the basis for G-Banding

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What percentage of the human genome is translated?

A

~1.5%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What percentage of the euchromatic human genome is made up of genes?

A

~20-25%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What percentage of the euchromatic human genome is made up of single copy sequences?

A

~50%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What percentage of the euchromatic human genome is made up of repetitive DNA (repeated hundreds to millions of times)?

A

~40-50%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What percentage of the human genome is derived from segmental duplications?

A

~5%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

How many cross-over events per pair of homologs?

A

~2-3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What percentage of spontaneous abortions are due to aneuploidy?

A

50-60%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

How common is Down Syndrome?

A

1/800 to 1/900 live births, though risk increases with maternal age.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

How common is Trisomy 18?

A

1/8000 births with 90% perinatal lethality

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is a significant LOD (Log of Odds) Score?

A

Greater than 3.0

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What percentage of drugs are metabolized by enzymes encoded for in the CYP 450 gene family.

A

~90%

17
Q

Where do adverse drug reactions sit on the list of leading causes of death

A

4th to 6th

18
Q

What is the incidence of Down Syndrome?

A

1/700 live births

19
Q

What is the frequency of chromosome missegregation?

A

2-4x10^-2/cell division

20
Q

What is the frequency of chromosome rearrangement?

A

6x10^-4/cell division

21
Q

What is the frequency of base pair mutation?

A

10^-5 to 10^-6/locus/generation

22
Q

How frequent is a new mutation in an offspring’s genome as compared to the parents

A

1/40 people

M2M (3 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions